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10.1016/j.stem.2015.12.012

http://scihub22266oqcxt.onion/10.1016/j.stem.2015.12.012
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C5409508!5409508!26748755
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suck abstract from ncbi


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pmid26748755      Cell+Stem+Cell 2016 ; 18 (1): 39-52
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  • Material Cues as Potent Regulators of Epigenetics and Stem Cell Function #MMPMID26748755
  • Crowder SW; Leonardo V; Whittaker T; Papathanasiou P; Stevens MM
  • Cell Stem Cell 2016[Jan]; 18 (1): 39-52 PMID26748755show ga
  • Biophysical signals act as potent regulators of stem cell function, lineage commitment, and epigenetic status. In recent years, synthetic biomaterials have been used to study a wide range of outside-in signaling events, and it is now well appreciated that material cues modulate the epigenetic status of cells. Here, we review the role of extracellular signals in guiding stem cell behavior via epigenetic regulation, and stress the role of physicochemical material properties as an often-overlooked modulator of intracellular signaling. We also highlight promising new research tools for ongoing interrogation of the stem cell-material interface.
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