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10.1186/s13059-017-1212-4 http://scihub22266oqcxt.onion/10.1186/s13059-017-1212-4 C5408830!5408830!28449691     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28449691&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genome+Biol 2017 ; 18 (ä): ä Nephropedia Template TP {{tp|p=28449691|t=2017. The impact of rare and low-frequency genetic variants in common disease |pdf=|usr=}}{{28449691}} gab.com Text The impact of rare and low-frequency genetic variants in common disease JO: Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=28449691 #FOAvip Despite thousands of genetic loci identified to date, a large proportion of genetic variation predisposing to complex disease and traits remains unaccounted for. Advances in sequencing technology enable focused explorations on the contribution of low-frequency and rare variants to human traits. Here we review experimental approaches and current knowledge on the contribution of these genetic variants in complex disease and discuss challenges and opportunities for personalised medicine.Electronic supplementary material: The online version of this article (doi:10.1186/s13059-017-1212-4) contains supplementary material, which is available to authorized users. Twit Text FOAVip The impact of rare and low-frequency genetic variants in common disease ????Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=28449691 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28449691 #FOAvip English Wikipedia <ref>{{Cite pmid|28449691}}</ref> The impact of rare and low-frequency genetic variants in common disease #MMPMID28449691 Bomba L; Walter K; Soranzo N Genome Biol 2017[]; 18 (ä): ä PMID28449691show ga Despite thousands of genetic loci identified to date, a large proportion of genetic variation predisposing to complex disease and traits remains unaccounted for. Advances in sequencing technology enable focused explorations on the contribution of low-frequency and rare variants to human traits. Here we review experimental approaches and current knowledge on the contribution of these genetic variants in complex disease and discuss challenges and opportunities for personalised medicine.Electronic supplementary material: The online version of this article (doi:10.1186/s13059-017-1212-4) contains supplementary material, which is available to authorized users. äThe impact of rare and low-frequency genetic variants in common diseas(epmc).pdf DeepDyve Pubget Overpricing