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10.1002/art.40064 http://scihub22266oqcxt.onion/10.1002/art.40064 C5407906!5407906 !28382787     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28382787 &cmd=llinks): Failed to open stream: HTTP request failed! 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69 (5 ): 898-910 Nephropedia Template TP {{tp|p=28382787 |t=2017. 2016 American College of Rheumatology/European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative |pdf=|usr=}}{{28382787 }} gab.com Text 2016 American College of Rheumatology/European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative JO: Arthritis Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=28382787 #FOAvip OBJECTIVE: To develop response criteria for adult dermatomyositis (DM) and polymyositis (PM). METHODS: Expert surveys, logistic regression, and conjoint analysis were used to develop 287 definitions using core set measures. Myositis experts rated greater improvement among multiple pairwise scenarios in conjoint analysis surveys, where different levels of improvement in 2 core set measures were presented. The PAPRIKA (Potentially All Pairwise Rankings of All Possible Alternatives) method determined the relative weights of core set measures and conjoint analysis definitions. The performance characteristics of the definitions were evaluated on patient profiles using expert consensus (gold standard) and were validated using data from a clinical trial. The nominal group technique was used to reach consensus. RESULTS: Consensus was reached for a conjoint analysis-based continuous model using absolute percent change in core set measures (physician, patient, and extramuscular global activity, muscle strength, Health Assessment Questionnaire, and muscle enzyme levels). A total improvement score (range 0-100), determined by summing scores for each core set measure, was based on improvement in and relative weight of each core set measure. Thresholds for minimal, moderate, and major improvement were ?20, ?40, and ?60 points in the total improvement score. The same criteria were chosen for juvenile DM, with different improvement thresholds. Sensitivity and specificity in DM/PM patient cohorts were 85% and 92%, 90% and 96%, and 92% and 98% for minimal, moderate, and major improvement, respectively. Definitions were validated in the clinical trial analysis for differentiating the physician rating of improvement (P?<?0.001). CONCLUSION: The response criteria for adult DM/PM consisted of the conjoint analysis model based on absolute percent change in 6 core set measures, with thresholds for minimal, moderate, and major improvement. Twit Text FOAVip 2016 American College of Rheumatology/European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative ????Arthritis Rheumatol http://www.kidney.de/pget.php?&tw=1&pmid=28382787 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28382787 #FOAvip English Wikipedia <ref>{{Cite pmid|28382787 }}</ref> 2016 American College of Rheumatology/European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative #MMPMID28382787 Aggarwal R ; Rider LG ; Ruperto N ; Bayat N ; Erman B ; Feldman BM ; Oddis CV ; Amato AA ; Chinoy H ; Cooper RG ; Dastmalchi M ; Fiorentino D ; Isenberg D ; Katz JD ; Mammen A ; de Visser M ; Ytterberg SR ; Lundberg IE ; Chung L ; Danko K ; García-De la Torre I ; Song YW ; Villa L ; Rinaldi M ; Rockette H ; Lachenbruch PA ; Miller FW ; Vencovsky J Arthritis Rheumatol 2017[May]; 69 (5 ): 898-910 PMID28382787 show ga OBJECTIVE: To develop response criteria for adult dermatomyositis (DM) and polymyositis (PM). METHODS: Expert surveys, logistic regression, and conjoint analysis were used to develop 287 definitions using core set measures. Myositis experts rated greater improvement among multiple pairwise scenarios in conjoint analysis surveys, where different levels of improvement in 2 core set measures were presented. The PAPRIKA (Potentially All Pairwise Rankings of All Possible Alternatives) method determined the relative weights of core set measures and conjoint analysis definitions. The performance characteristics of the definitions were evaluated on patient profiles using expert consensus (gold standard) and were validated using data from a clinical trial. The nominal group technique was used to reach consensus. RESULTS: Consensus was reached for a conjoint analysis-based continuous model using absolute percent change in core set measures (physician, patient, and extramuscular global activity, muscle strength, Health Assessment Questionnaire, and muscle enzyme levels). A total improvement score (range 0-100), determined by summing scores for each core set measure, was based on improvement in and relative weight of each core set measure. Thresholds for minimal, moderate, and major improvement were ?20, ?40, and ?60 points in the total improvement score. The same criteria were chosen for juvenile DM, with different improvement thresholds. Sensitivity and specificity in DM/PM patient cohorts were 85% and 92%, 90% and 96%, and 92% and 98% for minimal, moderate, and major improvement, respectively. Definitions were validated in the clinical trial analysis for differentiating the physician rating of improvement (P? |Alanine Transaminase/metabolism [MESH] |Antirheumatic Agents/*therapeutic use [MESH] |Aspartate Aminotransferases/metabolism [MESH] |Creatine Kinase/metabolism [MESH] |Dermatomyositis/*drug therapy/metabolism/physiopathology [MESH] |Europe [MESH] |Fructose-Bisphosphate Aldolase/metabolism [MESH] |Humans [MESH] |L-Lactate Dehydrogenase/metabolism [MESH] |Logistic Models [MESH] |Muscle Strength [MESH] |Outcome Assessment, Health Care [MESH] |Patient Reported Outcome Measures [MESH] |Polymyositis/drug therapy/metabolism/physiopathology [MESH] |Rheumatology [MESH] |Societies, Medical [MESH] |Surveys and Questionnaires [MESH] |Treatment Outcome [MESH]2016 American College of Rheumatology/European League Against Rheumati(epmc).pdf DeepDyve Pubget Overpricing