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10.3390/cancers9040036 http://scihub22266oqcxt.onion/10.3390/cancers9040036 C5406711!5406711!28425953     free     free     free       Cancers+(Basel) 2017 ; 9 (4): ä Nephropedia Template TP {{tp|p=28425953|t=2017. Cancer Chemotherapy Specific to Acidic Nests |pdf=|usr=}}{{28425953}} gab.com Text Cancer Chemotherapy Specific to Acidic Nests JO: Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28425953 #FOAvip The realization of cancer therapeutics specific to cancer cells with less of an effect on normal tissues is our goal. Many trials have been carried out for this purpose, but this goal is still far from being realized. It was found more than 80 years ago that solid cancer nests are acidified, but in vitro studies under acidic conditions have not been extensively studied. Recently, in vitro experiments under acidic conditions were started and anti-cancer drugs specific to acidic areas have been identified. Many genes have been reported to be expressed at a high level under acidic conditions, and such genes may be potent targets for anti-cancer drugs specific to acidic nests. In this review article, recent in vitro, in vivo, and clinical achievements in anti-cancer drugs with marked efficacy under acidic conditions are summarized, and the clinical use of anti-cancer drugs specific to acidic nests is discussed. Twit Text FOAVip Cancer Chemotherapy Specific to Acidic Nests ????Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28425953 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28425953 #FOAvip English Wikipedia <ref>{{Cite pmid|28425953}}</ref> Cancer Chemotherapy Specific to Acidic Nests #MMPMID28425953 Kobayashi H Cancers (Basel) 2017[Apr]; 9 (4): ä PMID28425953show ga The realization of cancer therapeutics specific to cancer cells with less of an effect on normal tissues is our goal. Many trials have been carried out for this purpose, but this goal is still far from being realized. It was found more than 80 years ago that solid cancer nests are acidified, but in vitro studies under acidic conditions have not been extensively studied. Recently, in vitro experiments under acidic conditions were started and anti-cancer drugs specific to acidic areas have been identified. Many genes have been reported to be expressed at a high level under acidic conditions, and such genes may be potent targets for anti-cancer drugs specific to acidic nests. In this review article, recent in vitro, in vivo, and clinical achievements in anti-cancer drugs with marked efficacy under acidic conditions are summarized, and the clinical use of anti-cancer drugs specific to acidic nests is discussed. äCancer Chemotherapy Specific to Acidic Nests (epmc).pdf DeepDyve Pubget Overpricing