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10.18240/ijo.2017.04.23 http://scihub22266oqcxt.onion/10.18240/ijo.2017.04.23 C5406646!5406646!28503441     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Ophthalmol 2017 ; 10 (4): 646-51 Nephropedia Template TP {{tp|p=28503441|t=2017. Applications of CRISPR/Cas9 in retinal degenerative diseases |pdf=|usr=}}{{28503441}} gab.com Text Applications of CRISPR/Cas9 in retinal degenerative diseases JO: Int J Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=28503441 #FOAvip Gene therapy is a potentially effective treatment for retinal degenerative diseases. Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system has been developed as a new genome-editing tool in ophthalmic studies. Recent advances in researches showed that CRISPR/Cas9 has been applied in generating animal models as well as gene therapy in vivo of retinitis pigmentosa (RP) and leber congenital amaurosis (LCA). It has also been shown as a potential attempt for clinic by combining with other technologies such as adeno-associated virus (AAV) and induced pluripotent stem cells (iPSCs). In this review, we highlight the main points of further prospect of using CRISPR/Cas9 in targeting retinal degeneration. We also emphasize the potential applications of this technique in treating retinal degenerative diseases. Twit Text FOAVip Applications of CRISPR/Cas9 in retinal degenerative diseases ????Int J Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=28503441 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28503441 #FOAvip English Wikipedia <ref>{{Cite pmid|28503441}}</ref> Applications of CRISPR/Cas9 in retinal degenerative diseases #MMPMID28503441 Peng YQ; Tang LS; Yoshida S; Zhou YD Int J Ophthalmol 2017[]; 10 (4): 646-51 PMID28503441show ga Gene therapy is a potentially effective treatment for retinal degenerative diseases. Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) system has been developed as a new genome-editing tool in ophthalmic studies. Recent advances in researches showed that CRISPR/Cas9 has been applied in generating animal models as well as gene therapy in vivo of retinitis pigmentosa (RP) and leber congenital amaurosis (LCA). It has also been shown as a potential attempt for clinic by combining with other technologies such as adeno-associated virus (AAV) and induced pluripotent stem cells (iPSCs). In this review, we highlight the main points of further prospect of using CRISPR/Cas9 in targeting retinal degeneration. We also emphasize the potential applications of this technique in treating retinal degenerative diseases. äApplications of CRISPR/Cas9 in retinal degenerative diseases (epmc).pdf DeepDyve Pubget Overpricing