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10.1186/s12882-017-0561-2 http://scihub22266oqcxt.onion/10.1186/s12882-017-0561-2 C5405476!5405476 !28446143     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28446143 &cmd=llinks): Failed to open stream: HTTP request failed! 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IgG4-related membranous glomerulonephritis and generalized lymphadenopathy without pancreatitis: a case report |pdf=|usr=}}{{28446143 }} gab.com Text IgG4-related membranous glomerulonephritis and generalized lymphadenopathy without pancreatitis: a case report JO: BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28446143 #FOAvip BACKGROUND: IgG4-related disease is a recently described pathologic entity. This is the case of a patient with nephrotic syndrome and lymphadenopathy due to IgG4-related disease. Such a kidney involvement is quite peculiar and has only been described a few times recently. Renal biopsy showed a glomerular involvement with membranous glomerulonephritis in association with a tubulo-interstitial nephropathy. Moreover, the patient was not suffering from pancreatitis. CASE PRESENTATION: The patient is a middle-aged man of Moroccan origin. He has developed recurrent episodes of diffuse lymphadenopathies, renal failure and nephrotic syndrome. Renal biopsies showed membranous glomerulonephritis. DISCUSSION AND CONCLUSION: The diagnostic approach of this atypical presentation is discussed in this case report as well as diagnostic criteria, therapeutic strategies, biomarkers and pathophysiology of IgG4-related disease. IgG4-related membranous glomerulonephritis is a well-established cause of membranous glomerulonephritis. It must be sought after in every patient with a previous diagnosis of IgG4-related disease and in every patient with this histological finding on renal biopsy. Corticoids are still the first-line treatment of IgG4-related disease. New therapeutic strategies are needed to avoid glucocorticoids long term side-effects. Interestingly, the patient was prescribed cyclophosphamide in addition to glucocorticoids for an immune thrombocytopenia. This treatment had a very good impact on his IgG4-related disease. Twit Text FOAVip IgG4-related membranous glomerulonephritis and generalized lymphadenopathy without pancreatitis: a case report ????BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=28446143 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28446143 #FOAvip English Wikipedia <ref>{{Cite pmid|28446143 }}</ref> IgG4-related membranous glomerulonephritis and generalized lymphadenopathy without pancreatitis: a case report #MMPMID28446143 Huart J ; Grosch S ; Bovy C ; Moutschen M ; Krzesinski JM BMC Nephrol 2017[Apr]; 18 (1 ): 139 PMID28446143 show ga BACKGROUND: IgG4-related disease is a recently described pathologic entity. This is the case of a patient with nephrotic syndrome and lymphadenopathy due to IgG4-related disease. Such a kidney involvement is quite peculiar and has only been described a few times recently. Renal biopsy showed a glomerular involvement with membranous glomerulonephritis in association with a tubulo-interstitial nephropathy. Moreover, the patient was not suffering from pancreatitis. CASE PRESENTATION: The patient is a middle-aged man of Moroccan origin. He has developed recurrent episodes of diffuse lymphadenopathies, renal failure and nephrotic syndrome. Renal biopsies showed membranous glomerulonephritis. DISCUSSION AND CONCLUSION: The diagnostic approach of this atypical presentation is discussed in this case report as well as diagnostic criteria, therapeutic strategies, biomarkers and pathophysiology of IgG4-related disease. IgG4-related membranous glomerulonephritis is a well-established cause of membranous glomerulonephritis. It must be sought after in every patient with a previous diagnosis of IgG4-related disease and in every patient with this histological finding on renal biopsy. Corticoids are still the first-line treatment of IgG4-related disease. New therapeutic strategies are needed to avoid glucocorticoids long term side-effects. Interestingly, the patient was prescribed cyclophosphamide in addition to glucocorticoids for an immune thrombocytopenia. This treatment had a very good impact on his IgG4-related disease. |Adult [MESH] |Diagnosis, Differential [MESH] |Glomerulonephritis, Membranous/*diagnosis/*drug therapy/immunology [MESH] |Glucocorticoids/*therapeutic use [MESH] |Humans [MESH] |Immunoglobulin G/*immunology [MESH] |Lymphadenopathy/*diagnosis/*drug therapy/immunology [MESH] |Male [MESH] |Pancreatitis/diagnosis/drug therapy/immunology [MESH]IgG4-related membranous glomerulonephritis and generalized lymphadenop(epmc).pdf DeepDyve Pubget Overpricing