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10.2174/1570163814666170117120005

http://scihub22266oqcxt.onion/10.2174/1570163814666170117120005
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suck abstract from ncbi


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pmid28124597      Curr+Drug+Discov+Technol 2017 ; 14 (2): 121-6
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  • Pimping up Drugs Recovered, Superannuated and Under Exploited Drugs - An Introduction to the Basics of Drug Reprofiling #MMPMID28124597
  • Dilly SJ; Morris GS
  • Curr Drug Discov Technol 2017[Jun]; 14 (2): 121-6 PMID28124597show ga
  • Drug development has moved along way forward from the days of with doctors peddling cauldrons of herbs and spices, however, the process can still miss opportunities for full exploitation of a drug?s potential. Drug reprofiling provides a chance for an established or a forgotten drug to move into a new area of therapy, whether related to the known effects or in a completely new area. In an era of environmental awareness and spiraling costs for traditional drug development, a strategy to squeeze every benefit out of drugs with known safety, tolerability and pharmacological parameters must be a strategically sound desire. We explore examples of success in reprofiling, draw comparisons between techniques, and finally provide two examples from the Valirx plc development pipeline currently undergoing the process.
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