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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Exp+Ther+Med 2017 ; 13 (3): 1151-4 Nephropedia Template TP
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VanWyk-Grumbach syndrome in a male pediatric patient: A rare case report and literature review #MMPMID28450956
Zhang S; Yang J; Zheng R; Jiang L; Wei Y; Liu G
Exp Ther Med 2017[Mar]; 13 (3): 1151-4 PMID28450956show ga
Primary hypothyroidism usually leads to retardation of linear growth and delay or even arrest of puberty in juvenile patients. In rare cases, pediatric patients with hypothyroidism may present with signs of VanWyk-Grumbach's syndrome (VWGS), which includes juvenile hypothyroidism, delayed bone age and pseudoprecocious puberty. The present study reported on a rare case of VWGS and other complications, including obesity, short stature, hepatomegaly and pituitary hyperplasia. In addition, a comprehensive literature review was performed to illustrate the treatment and outcome of VWGS in pediatric patients. The present study contributed to the current knowledge regarding the diagnosis and treatment of VWGS in pediatric patients.