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10.3892/ol.2017.5733 http://scihub22266oqcxt.onion/10.3892/ol.2017.5733 C5403191!5403191!28454418     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncol+Lett 2017 ; 13 (4): 2449-53 Nephropedia Template TP {{tp|p=28454418|t=2017. Epigenetic silencing of protocadherin 10 in colorectal cancer |pdf=|usr=}}{{28454418}} gab.com Text Epigenetic silencing of protocadherin 10 in colorectal cancer JO: Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=28454418 #FOAvip Colorectal cancer (CRC) is one of the most common types of malignant tumor in the world and occurs through a multi-step process resulting from the accumulation of genetic and epigenetic alterations of the genome. Although the molecular mechanisms of the pathogenesis of CRC remain unclear, the inactivation of tumor suppressor genes (TSGs) through promoter methylation serves an important role. Aberrant methylation is a well-defined marker of CRC. At present, the epigenetic silencing of protocadherin 10 (PCDH10) has been identified as an important TSG with key roles in colorectal carcinogenesis, invasion and metastasis as a frequent and early event. Advances in gene methylation detection in tumor tissues and body fluids have led to the development of non-invasive screening methods for CRC. The present study aimed to review the epigenetic alteration of PCDH10 in CRC development, and the potential of PCDH10 to be a non-invasive biomarker for CRC. Twit Text FOAVip Epigenetic silencing of protocadherin 10 in colorectal cancer ????Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=28454418 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28454418 #FOAvip English Wikipedia <ref>{{Cite pmid|28454418}}</ref> Epigenetic silencing of protocadherin 10 in colorectal cancer #MMPMID28454418 Zhong X; Shen H; Mao J; Zhang J; Han W Oncol Lett 2017[Apr]; 13 (4): 2449-53 PMID28454418show ga Colorectal cancer (CRC) is one of the most common types of malignant tumor in the world and occurs through a multi-step process resulting from the accumulation of genetic and epigenetic alterations of the genome. Although the molecular mechanisms of the pathogenesis of CRC remain unclear, the inactivation of tumor suppressor genes (TSGs) through promoter methylation serves an important role. Aberrant methylation is a well-defined marker of CRC. At present, the epigenetic silencing of protocadherin 10 (PCDH10) has been identified as an important TSG with key roles in colorectal carcinogenesis, invasion and metastasis as a frequent and early event. Advances in gene methylation detection in tumor tissues and body fluids have led to the development of non-invasive screening methods for CRC. The present study aimed to review the epigenetic alteration of PCDH10 in CRC development, and the potential of PCDH10 to be a non-invasive biomarker for CRC. äEpigenetic silencing of protocadherin 10 in colorectal cancer (epmc).pdf DeepDyve Pubget Overpricing