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10.2147/DDDT.S124273 http://scihub22266oqcxt.onion/10.2147/DDDT.S124273 C5402893!5402893!28458521     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Drug+Des+Devel+Ther 2017 ; 11 (ä): 1273-82 Nephropedia Template TP {{tp|p=28458521|t=2017. Cerebrolysin for functional recovery in patients with acute ischemic stroke: a meta-analysis of randomized controlled trials |pdf=|usr=}}{{28458521}} gab.com Text Cerebrolysin for functional recovery in patients with acute ischemic stroke: a meta-analysis of randomized controlled trials JO: Drug Des Devel Ther http://www.kidney.de/pget.php?&tw=1&pmid=28458521 #FOAvip Cerebrolysin has been shown to have an inconsistent efficacy on functional recovery in patients with acute ischemic stroke (AIS). The present meta-analysis aims to evaluate the value of cerebrolysin and to explore the potential influencing factors. The main electronic databases, including MEDLINE, EMBASE, and the Cochrane Library, were searched. The primary outcome was functional recovery at Day 90. The secondary outcomes included mortality and adverse events. A total of 1,649 patients with AIS were pooled from six randomized controlled trials (RCTs). Cerebrolysin had no significant effect on functional recovery at Day 90 compared with the effect of placebo as shown by the modified Rankin Scale response (relative risk [RR] 1.33, 95% confidence interval [CI] 0.79?2.24, P=0.28), National Institutes of Health Stroke Scale response (RR 1.03, 95% CI 0.83?1.28, P=0.77), and Barthel Index response (RR 0.95, 95% CI 0.84?1.08, P=0.44). In safety analysis, cerebrolysin did not increase the risk of adverse events (RR 0.98, 95% CI 0.88?1.09, P=0.67), risk of serious adverse events (RR 1.20, 95% CI 0.86?1.66, P=0.29), or the mortality rate (RR 0.86, 95% CI 0.57?1.31, P=0.49). In conclusion, routine administration of cerebrolysin to patients with AIS cannot be supported by the available evidence from RCTs. Twit Text FOAVip Cerebrolysin for functional recovery in patients with acute ischemic stroke: a meta-analysis of randomized controlled trials ????Drug Des Devel Ther http://www.kidney.de/pget.php?&tw=1&pmid=28458521 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28458521 #FOAvip English Wikipedia <ref>{{Cite pmid|28458521}}</ref> Cerebrolysin for functional recovery in patients with acute ischemic stroke: a meta-analysis of randomized controlled trials #MMPMID28458521 Wang Z; Shi L; Xu S; Zhang J Drug Des Devel Ther 2017[]; 11 (ä): 1273-82 PMID28458521show ga Cerebrolysin has been shown to have an inconsistent efficacy on functional recovery in patients with acute ischemic stroke (AIS). The present meta-analysis aims to evaluate the value of cerebrolysin and to explore the potential influencing factors. The main electronic databases, including MEDLINE, EMBASE, and the Cochrane Library, were searched. The primary outcome was functional recovery at Day 90. The secondary outcomes included mortality and adverse events. A total of 1,649 patients with AIS were pooled from six randomized controlled trials (RCTs). Cerebrolysin had no significant effect on functional recovery at Day 90 compared with the effect of placebo as shown by the modified Rankin Scale response (relative risk [RR] 1.33, 95% confidence interval [CI] 0.79?2.24, P=0.28), National Institutes of Health Stroke Scale response (RR 1.03, 95% CI 0.83?1.28, P=0.77), and Barthel Index response (RR 0.95, 95% CI 0.84?1.08, P=0.44). In safety analysis, cerebrolysin did not increase the risk of adverse events (RR 0.98, 95% CI 0.88?1.09, P=0.67), risk of serious adverse events (RR 1.20, 95% CI 0.86?1.66, P=0.29), or the mortality rate (RR 0.86, 95% CI 0.57?1.31, P=0.49). In conclusion, routine administration of cerebrolysin to patients with AIS cannot be supported by the available evidence from RCTs. äCerebrolysin for functional recovery in patients with acute ischemic s(epmc).pdf DeepDyve Pubget Overpricing