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2016 ; 31
(1
): 203-226
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The Intimate Geographies of Panic Disorder: Parsing Anxiety through
Psychopharmacological Dissection
#MMPMID28446834
Callard F
Osiris
2016[]; 31
(1
): 203-226
PMID28446834
show ga
The category of panic disorder was significantly indebted to early
psychopharmacological experiments (in the late 1950s and early 1960s) by the
psychiatrist Donald Klein, in collaboration with Max Fink. Klein's technique of
"psychopharmacological dissection" underpinned his transformation of clinical
accounts of anxiety and was central in effecting the shift from agoraphobic
anxiety (with its spatial imaginary of city squares and streets) to panic. This
technique disaggregated the previously unitary affect of anxiety-as advanced in
psychoanalytic accounts-into two physiological and phenomenological kinds.
"Psychopharmacological dissection" depended on particular modes of clinical
observation to assess drug action and to interpret patient behavior. The
"intimate geographies" out of which panic disorder emerged comprised both the
socio-spatial dynamics of observation on the psychiatric ward and Klein's use of
John Bowlby's model of separation anxiety-as it played out between the dyad of
infant and mother-to interpret his adult patients' affectively disordered
behavior. This essay, in offering a historical geography of mid-twentieth-century
anxiety and panic, emphasizes the importance of socio-spatial setting in
understanding how clinical and scientific experimentation opens up new ways in
which affects can be expressed, shaped, observed, and understood.