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10.1038/srep46652 http://scihub22266oqcxt.onion/10.1038/srep46652 C5402387!5402387!28436448     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 284.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28436448|t=2017. Elevated circulating levels of the interferon-??induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still?s disease |pdf=|usr=}}{{28436448}} gab.com Text Elevated circulating levels of the interferon- induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still s disease JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28436448 #FOAvip C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 are produced in response to interferon-? (IFN-?) and trigger inflammation with the accumulation of activated lymphocytes. It appears that these chemokines could play a role in the pathogenesis of adult-onset Still?s disease (AOSD). Therefore, we investigated the associations between the levels of these chemokine and clinical manifestations in patients with active AOSD. Serum levels of IFN-?, CXCL9, CXCL10 and CXCL11 were determined using enzyme-linked immunosorbent assays. IFN-? levels were higher in AOSD patients than in rheumatoid arthritis (RA) patients (p?=?0.001) or healthy controls (HCs) (p?=?0.032). AOSD patients also exhibited higher levels of CXCL9, CXCL10, and CXCL11 compared with RA patients (p?<?0.001) and HCs (p?<?0.001). In follow-up AOSD patients after treatment with corticosteroid, the levels of CXCL9, CXCL10 and CXCL11 fell significantly, whereas IFN-? levels were not significantly different. On immunohistochemistry, the percentage of CXCL10-positive inflammatory cells was higher in skin biopsy samples from AOSD patients than in those from normal control (p?=?0.012), eczema (p?=?0.019), and psoriasis (p?=?0.009) groups. Levels of the IFN-??induced chemokines, CXCL9, CXCL10 and CXCL11, were elevated and correlated with several disease activity markers. These interferon-??induced chemokines may contribute to inflammatory responses and skin manifestations in AOSD. Twit Text FOAVip Elevated circulating levels of the interferon- induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still s disease ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28436448 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28436448 #FOAvip English Wikipedia <ref>{{Cite pmid|28436448}}</ref> Elevated circulating levels of the interferon-??induced chemokines are associated with disease activity and cutaneous manifestations in adult-onset Still?s disease #MMPMID28436448 Han JH; Suh CH; Jung JY; Ahn MH; Han MH; Kwon JE; Yim H; Kim HA Sci Rep 2017[]; 7 (ä): ä PMID28436448show ga C-X-C motif chemokine 9 (CXCL9), CXCL10, and CXCL11 are produced in response to interferon-? (IFN-?) and trigger inflammation with the accumulation of activated lymphocytes. It appears that these chemokines could play a role in the pathogenesis of adult-onset Still?s disease (AOSD). Therefore, we investigated the associations between the levels of these chemokine and clinical manifestations in patients with active AOSD. Serum levels of IFN-?, CXCL9, CXCL10 and CXCL11 were determined using enzyme-linked immunosorbent assays. IFN-? levels were higher in AOSD patients than in rheumatoid arthritis (RA) patients (p?=?0.001) or healthy controls (HCs) (p?=?0.032). AOSD patients also exhibited higher levels of CXCL9, CXCL10, and CXCL11 compared with RA patients (p? äElevated circulating levels of the interferon-??induced chemokines are(epmc).pdf DeepDyve Pubget Overpricing