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Membranous nephropathy associated with hepatitis C virus infection treated with
corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of
literature
#MMPMID28223549
Weng Q
; Li X
; Ren H
; Xie J
; Pan X
; Xu J
; Chen N
Oncotarget
2017[Mar]; 8
(13
): 22299-22303
PMID28223549
show ga
BACKGROUND: Membranous nephropathy (MN) is the most common cause of nephrotic
syndrome in adults. As many clinical cases have reported, it may be associated
with hepatitis C virus (HCV) infection. Antiviral therapy can be various. CASE
SUMMARY: We report a case of patient with chronic HCV infection and MN, who
presented with was proteinuria. He was treated with ledipasvir and sofosbuvir
(Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free.
CONCLUSION: We have reported this case to provide insight into whether
Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis.
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