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10.18632/oncotarget.15473 http://scihub22266oqcxt.onion/10.18632/oncotarget.15473 C5400563!5400563 !28423500     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28423500 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Oncotarget 2017 ; 8 (13 ): 21031-21043 Nephropedia Template TP {{tp|p=28423500 |t=2017. The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration |pdf=|usr=}}{{28423500 }} gab.com Text The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28423500 #FOAvip Hesperetin has been suggested to be involved in bone strength. We aimed to investigate the effects of hesperetin on the osteogenic differentiation of human mesenchymal stem cells and its related mechanisms. We showed that hesperetin promoted osteogenic differentiation of human mesenchymal stem cells in vitro. It potentially exerts its effects via the ERK and Smad signaling pathways. Using a rat osteotomy model, we showed that human mesenchymal stem cells combined with a hesperetin/gelatin sponge scaffold resulted in accelerated fracture healing in vivo. Due to the low cost of hesperetin, it could be used as a growth factor for bone tissue engineering or surgical fracture treatment. Twit Text FOAVip The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28423500 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28423500 #FOAvip English Wikipedia <ref>{{Cite pmid|28423500 }}</ref> The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration #MMPMID28423500 Xue D ; Chen E ; Zhang W ; Gao X ; Wang S ; Zheng Q ; Pan Z ; Li H ; Liu L Oncotarget 2017[Mar]; 8 (13 ): 21031-21043 PMID28423500 show ga Hesperetin has been suggested to be involved in bone strength. We aimed to investigate the effects of hesperetin on the osteogenic differentiation of human mesenchymal stem cells and its related mechanisms. We showed that hesperetin promoted osteogenic differentiation of human mesenchymal stem cells in vitro. It potentially exerts its effects via the ERK and Smad signaling pathways. Using a rat osteotomy model, we showed that human mesenchymal stem cells combined with a hesperetin/gelatin sponge scaffold resulted in accelerated fracture healing in vivo. Due to the low cost of hesperetin, it could be used as a growth factor for bone tissue engineering or surgical fracture treatment. |Animals [MESH] |Apoptosis/drug effects [MESH] |Bone Regeneration/drug effects/*physiology [MESH] |Cell Differentiation/drug effects [MESH] |Cell Movement/drug effects [MESH] |Cell Proliferation/drug effects [MESH] |Cells, Cultured [MESH] |Hesperidin/*pharmacology [MESH] |Humans [MESH] |Male [MESH] |Mesenchymal Stem Cells/*cytology/drug effects/metabolism [MESH] |Osteogenesis/drug effects/*physiology [MESH] |Phosphorylation/drug effects [MESH] |Rats [MESH] |Rats, Sprague-Dawley [MESH] |Signal Transduction [MESH]The role of hesperetin on osteogenesis of human mesenchymal stem cells(epmc).pdf DeepDyve Pubget Overpricing