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suck abstract from ncbi


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pmid28250303      Intern+Med 2017 ; 56 (5): 545-9
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  • Non-uniform Progression of Chronic Tubulointerstitial Nephritis and Widespread Nephrocalcification in a Patient with Anorexia Nervosa #MMPMID28250303
  • Hasegawa S; Shibata M; Mochizuki M; Katsuki T; Tada M; Hinoshita F
  • Intern Med 2017[Mar]; 56 (5): 545-9 PMID28250303show ga
  • Although patients with anorexia nervosa (anorexia) are known to show tubulointerstitial nephritis (TIN), the pathophysiology of its progression is not fully understood. We herein report a 31-year-old woman with anorexia who showed acute exacerbation of chronic kidney disease. Renal biopsy showed non-uniform chronic TIN; some areas were obsolete lesions and other areas were active lesions. In addition, many calcium-containing crystals were widely deposited in the distal tubules. The results suggest that chronic TIN in the setting of anorexia does not uniformly progress and that not only TIN but also widespread calcification of distal tubules might aggravate the renal function of anorexia patients.
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