Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28496630
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Atr+Fibrillation
2009 ; 2
(1
): 191
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Evolution of Paroxysmal Atrial Fibrillation to Persistent or Permanent Atrial
Fibrillation: Predictors of Progression
#MMPMID28496630
Pillarisetti J
; Patel A
; Boc K
; Bommana S
; Sawers Y
; Vanga S
; Sayana H
; Chen W
; Nath J
; Vacek J
; Lakkireddy D
J Atr Fibrillation
2009[Jun]; 2
(1
): 191
PMID28496630
show ga
Introduction: Paroxysmal atrial fibrillation (PAF) eventually progresses to
persistent and permanent AF. The predictors of progression from PAF to persistent
and permanent AF are poorly understood. Methods: Electronic medical records of
437 patients with PAF were reviewed in a retrospective cohort study. Patients
were followed in time and progression to persistent/permanent AF was recorded.
Demographic, clinical and echocardiographic information was collected. A logistic
regression analysis was performed to identify predictors of progression to
persistent/permanent AF. Results: Over a mean duration of 57.3±55.9 months, 32.4%
of patients progressed to persistent/permanent AF. Mean age of the population was
67.9±13.4 years with 57% males and 92% Caucasian. Univariate analysis identified
higher body higher mass index (BMI), cardiomyopathy, diabetes, valvular heart
disease (VHD), larger left atrial size (LA) and higher pulmonary artery pressure
as predictors of progression. Multivariate logistic regression analysis larger
left atrial size (OR 1.46, CI 1.05-2.04, P 0.002), cardiomyopathy (OR 2, CI 1.1-
3.3, P 0.003), and moderate to severe valvular heart disease (OR 3.3, CI 1.4-5, P
0.008) as significant predictors of progression to persistent/permanent AF.
Conclusions: Our study shows that PAF patients with larger LA, valvular heart
disease and cardiomyopathy predict progression of PAF to persistent/permanent AF.
Higher BMI and cardiomyopathy predicted progression to persistent AF while larger
LA size and VHD predicted progression to permanent AF.