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10.2147/EB.S94452

http://scihub22266oqcxt.onion/10.2147/EB.S94452
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C5398754!5398754!28539809
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pmid28539809      Eye+Brain 2016 ; 8 (ä): 141-6
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  • Wnt signaling pathway in retinal vascularization #MMPMID28539809
  • Drenser KA
  • Eye Brain 2016[]; 8 (ä): 141-6 PMID28539809show ga
  • Wnt-signaling, a ubiquitous pathway that directs differentiation, cell polarity, and tissue specificity, has been implicated as an important gene-expression pathway in retinal development. An increasing body of evidence supports the importance of Wnt-signaling, and specifically, norrin-mediated Wnt-signaling in retinal development and retinal maintenance. Gene mutations affecting the Wnt-signaling pathways result in a variety of inherited vitreoretinopathies. Additionally, there is growing evidence that prematurity and associated retinopathy are associated with alterations in the Wnt-signaling pathways. Further investigations may allow for improved diagnoses, management, and therapies in the future.
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