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10.1111/1756-185X.12901 http://scihub22266oqcxt.onion/10.1111/1756-185X.12901 C5396326!5396326!27451980     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Rheum+Dis 2016 ; 19 (12): 1216-25 Nephropedia Template TP {{tp|p=27451980|t=2016. Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies |pdf=|usr=}}{{27451980}} gab.com Text Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies JO: Int J Rheum Dis http://www.kidney.de/pget.php?&tw=1&pmid=27451980 #FOAvip Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here, the safety and efficacy data from five Phase 2 studies of tofacitinib in patients with RA are summarized. Tofacitinib 1?30 mg twice daily was investigated, as monotherapy and in combination with methotrexate, in patients with RA. Tofacitinib 20 mg once daily was investigated in one study. Tofacitinib 5 and 10 mg twice daily were selected for investigation in Phase 3 studies; therefore, the efficacy and safety of tofacitinib 5 and 10 mg twice daily in Phase 2 studies are the focus of this review. Tofacitinib ? 5 mg twice daily was efficacious in a dose?dependent manner, with statistically significant and clinically meaningful reductions in the signs and symptoms of RA and patient?reported outcomes. The safety profile was consistent across studies. The efficacy and safety profile of tofacitinib in Phase 2 studies supported its further investigation and the selection of tofacitinib 5 mg twice daily and tofacitinib 10 mg twice daily for evaluation in Phase 3 studies. Twit Text FOAVip Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies ????Int J Rheum Dis http://www.kidney.de/pget.php?&tw=1&pmid=27451980 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27451980 #FOAvip English Wikipedia <ref>{{Cite pmid|27451980}}</ref> Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies #MMPMID27451980 Fleischmann R; Kremer J; Tanaka Y; Gruben D; Kanik K; Koncz T; Krishnaswami S; Wallenstein G; Wilkinson B; Zwillich SH; Keystone E Int J Rheum Dis 2016[Dec]; 19 (12): 1216-25 PMID27451980show ga Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here, the safety and efficacy data from five Phase 2 studies of tofacitinib in patients with RA are summarized. Tofacitinib 1?30 mg twice daily was investigated, as monotherapy and in combination with methotrexate, in patients with RA. Tofacitinib 20 mg once daily was investigated in one study. Tofacitinib 5 and 10 mg twice daily were selected for investigation in Phase 3 studies; therefore, the efficacy and safety of tofacitinib 5 and 10 mg twice daily in Phase 2 studies are the focus of this review. Tofacitinib ? 5 mg twice daily was efficacious in a dose?dependent manner, with statistically significant and clinically meaningful reductions in the signs and symptoms of RA and patient?reported outcomes. The safety profile was consistent across studies. The efficacy and safety profile of tofacitinib in Phase 2 studies supported its further investigation and the selection of tofacitinib 5 mg twice daily and tofacitinib 10 mg twice daily for evaluation in Phase 3 studies. äEfficacy and safety of tofacitinib in patients with active rheumatoid (epmc).pdf DeepDyve Pubget Overpricing