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10.1038/srep46458

http://scihub22266oqcxt.onion/10.1038/srep46458
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C5396067!5396067!28422172
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suck abstract from ncbi


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pmid28422172      Sci+Rep 2017 ; 7 (ä): ä
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  • Transient elastography as a screening tool for liver fibrosis in a large hemodialysis population #MMPMID28422172
  • Cheng BC; Yen YH; Chen JF; Wu CK; Chang KC; Tseng PL; Tsai MC; Lin MT; Lin JT; Chen JB; Hu TH
  • Sci Rep 2017[]; 7 (ä): ä PMID28422172show ga
  • Metabolic syndrome, an etiological factor in non-alcoholic fatty liver disease (NAFLD), is often present in hemodialysis patients. Little is known about the prevalence of, and factors associated with, liver fibrosis in hemodialysis populations. We used transient elastography (TE) to investigate these phenomena. 659 patients treated with chronic hemodialysis were enrolled. We excluded those with excess alcohol intake, liver stiffness measurement (LSM) failure, or unreliable LSM values. LSM ?8.0?kPa was used as a cutoff suggesting clinically relevant fibrosis. Controlled attenuation parameter (CAP)???232.5?dB/m was used as a cutoff suggesting steatosis. 333 patients (50.5%) had steatosis, 159 (24.1%) had hepatitis B or C, and 149 (22.6%) had LSM ?8.0?kPa. In multivariable analyses, male gender (OR: 2.16; 95% CI: 1.29?3.63; P?=?0.004), overweight body habitus (OR:2.31; 95% CI: 1.35?3.94; P?=?0.002), high AST level (OR:1.08; 95% CI: 1.04?1.12; P?
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