Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28420349
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28420349
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMC+Med+Res+Methodol
2017 ; 17
(1
): 64
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Grey literature in systematic reviews: a cross-sectional study of the
contribution of non-English reports, unpublished studies and dissertations to the
results of meta-analyses in child-relevant reviews
#MMPMID28420349
Hartling L
; Featherstone R
; Nuspl M
; Shave K
; Dryden DM
; Vandermeer B
BMC Med Res Methodol
2017[Apr]; 17
(1
): 64
PMID28420349
show ga
BACKGROUND: Systematic reviews (SRs) are an important source of information about
healthcare interventions. A key component of a well-conducted SR is a
comprehensive literature search. There is limited evidence on the contribution of
non-English reports, unpublished studies, and dissertations and their impact on
results of meta-analyses. METHODS: Our sample included SRs from three Cochrane
Review Groups: Acute Respiratory Infections (ARI), Infectious Diseases (ID),
Developmental Psychosocial and Learning Problems (DPLP) (n?=?129). Outcomes
included: 1) proportion of reviews that searched for and included each study
type; 2) proportion of relevant studies represented by each study type; and 3)
impact on results and conclusions of the primary meta-analysis for each study
type. RESULTS: Most SRs searched for non-English studies; however, these were
included in only 12% of reviews and represented less than 5% of included studies.
There was a change in results in only four reviews (total sample?=?129); in two
cases the change did not have an impact on the statistical or clinical
significance of results. Most SRs searched for unpublished studies but the
majority did not include these (only 6%) and they represented 2% of included
studies. In most cases the impact of including unpublished studies was small; a
substantial impact was observed in one case that relied solely on unpublished
data. Few reviews in ARI (9%) and ID (3%) searched for dissertations compared to
65% in DPLP. Overall, dissertations were included in only nine SRs and
represented less than 2% of included studies. In the majority of cases the change
in results was negligible or small; in the case where a large change was noted,
the estimate was more conservative without dissertations. CONCLUSIONS: The
majority of SRs searched for non-English and unpublished studies; however, these
represented a small proportion of included studies and rarely impacted the
results and conclusions of the review. Inclusion of these study types may have an
impact in situations where there are few relevant studies, or where there are
questionable vested interests in the published literature. We found substantial
variation in whether SRs searched for dissertations; in most reviews that
included dissertations, these had little impact on results.