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10.1186/s12883-017-0842-1

http://scihub22266oqcxt.onion/10.1186/s12883-017-0842-1
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C5395768!5395768!28424054
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suck abstract from ncbi


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pmid28424054      BMC+Neurol 2017 ; 17 (ä): ä
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  • An unusual delusion of duplication in a patient affected by Dementia with Lewy bodies #MMPMID28424054
  • Solla P; Mura G; Cannas A; Floris G; Fonti D; Orofino G; Carta MG; Marrosu F
  • BMC Neurol 2017[]; 17 (ä): ä PMID28424054show ga
  • Background: Dementia with Lewy bodies (DLB) is the second most frequent diagnosis of progressive degenerative dementia in older people. Delusions are common features in DLB and, among them, Capgras syndrome represents the most frequent disturbance, characterized by the recurrent and transient belief that a familiar person, often a close family member or caregiver, has been replaced by an identical-looking imposter. However, other delusional conditions near to misidentification syndromes can occur in DLB patients and may represent a major psychiatric disorder, although rarely studied systematically. Case presentation: We reported on a female patient affected by DLB who presented with an unusual delusion of duplication. Referring to the female professional caregiver engaged by her relatives for her care, the patient constantly described the presence of two different female persons, with a disorder framed in the context of a delusion of duplication.A brain 99Tc-hexamethylpropyleneamineoxime SPECT was performed showing moderate hypoperfusion in both occipital lobes, and associated with marked decreased perfusion in parieto-fronto-temporal lobes bilaterally. Conclusions: An occipital hypoperfusion was identified, although in association with a marked global decrease of perfusion in the remaining lobes. The role of posterior lobes is certainly important in all misidentification syndromes where a natural dissociation between recognition and identification is present. Moreover, the concomitant presence of severe attentional and executive deficits evocative for a frontal syndrome and the marked global decrease of perfusion in the remaining lobes at the SPECT scan also suggest a possible dysfunction in an abnormal connectivity between anterior and posterior areas. Electronic supplementary material: The online version of this article (doi:10.1186/s12883-017-0842-1) contains supplementary material, which is available to authorized users.
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