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10.1007/s00018-015-1975-2 http://scihub22266oqcxt.onion/10.1007/s00018-015-1975-2 C5395663!5395663 !26126787     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26126787 &cmd=llinks): Failed to open stream: HTTP request failed! 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Mesenchymal-epithelial interactions during digestive tract development and epithelial stem cell regeneration |pdf=|usr=}}{{26126787 }} gab.com Text Mesenchymal-epithelial interactions during digestive tract development and epithelial stem cell regeneration JO: Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=26126787 #FOAvip The gastrointestinal tract develops from a simple and uniform tube into a complex organ with specific differentiation patterns along the anterior-posterior and dorso-ventral axes of asymmetry. It is derived from all three germ layers and their cross-talk is important for the regulated development of fetal and adult gastrointestinal structures and organs. Signals from the adjacent mesoderm are essential for the morphogenesis of the overlying epithelium. These mesenchymal-epithelial interactions govern the development and regionalization of the different gastrointestinal epithelia and involve most of the key morphogens and signaling pathways, such as the Hedgehog, BMPs, Notch, WNT, HOX, SOX and FOXF cascades. Moreover, the mechanisms underlying mesenchyme differentiation into smooth muscle cells influence the regionalization of the gastrointestinal epithelium through interactions with the enteric nervous system. In the neonatal and adult gastrointestinal tract, mesenchymal-epithelial interactions are essential for the maintenance of the epithelial regionalization and digestive epithelial homeostasis. Disruption of these interactions is also associated with bowel dysfunction potentially leading to epithelial tumor development. In this review, we will discuss various aspects of the mesenchymal-epithelial interactions observed during digestive epithelium development and differentiation and also during epithelial stem cell regeneration. Twit Text FOAVip Mesenchymal-epithelial interactions during digestive tract development and epithelial stem cell regeneration ????Cell Mol Life Sci http://www.kidney.de/pget.php?&tw=1&pmid=26126787 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26126787 #FOAvip English Wikipedia <ref>{{Cite pmid|26126787 }}</ref> Mesenchymal-epithelial interactions during digestive tract development and epithelial stem cell regeneration #MMPMID26126787 Le Guen L ; Marchal S ; Faure S ; de Santa Barbara P Cell Mol Life Sci 2015[Oct]; 72 (20 ): 3883-96 PMID26126787 show ga The gastrointestinal tract develops from a simple and uniform tube into a complex organ with specific differentiation patterns along the anterior-posterior and dorso-ventral axes of asymmetry. It is derived from all three germ layers and their cross-talk is important for the regulated development of fetal and adult gastrointestinal structures and organs. Signals from the adjacent mesoderm are essential for the morphogenesis of the overlying epithelium. These mesenchymal-epithelial interactions govern the development and regionalization of the different gastrointestinal epithelia and involve most of the key morphogens and signaling pathways, such as the Hedgehog, BMPs, Notch, WNT, HOX, SOX and FOXF cascades. Moreover, the mechanisms underlying mesenchyme differentiation into smooth muscle cells influence the regionalization of the gastrointestinal epithelium through interactions with the enteric nervous system. In the neonatal and adult gastrointestinal tract, mesenchymal-epithelial interactions are essential for the maintenance of the epithelial regionalization and digestive epithelial homeostasis. Disruption of these interactions is also associated with bowel dysfunction potentially leading to epithelial tumor development. In this review, we will discuss various aspects of the mesenchymal-epithelial interactions observed during digestive epithelium development and differentiation and also during epithelial stem cell regeneration. |Cell Communication [MESH] |Cell Differentiation [MESH] |Gastrointestinal Tract/cytology/embryology/metabolism [MESH] |Humans [MESH] |Intestinal Mucosa/cytology/*embryology/metabolism [MESH] |Mesoderm/cytology/*embryology/metabolism [MESH] |Myocytes, Smooth Muscle/cytology [MESH] |Signal Transduction [MESH]Mesenchymal-epithelial interactions during digestive tract development(epmc).pdf DeepDyve Pubget Overpricing