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10.1016/j.gene.2017.01.016 http://scihub22266oqcxt.onion/10.1016/j.gene.2017.01.016 C5394985!5394985!28122268     free     free     free       Gene 2017 ; 614 (ä): 8-14 Nephropedia Template TP {{tp|p=28122268|t=2017. Interluekin-17A (IL17A) |pdf=|usr=}}{{28122268}} gab.com Text Interluekin-17A (IL17A) JO: Gene http://www.kidney.de/pget.php?&tw=1&pmid=28122268 #FOAvip The discovery of the key roles of interleukin-17A (IL-17A) and IL-17A producing cells in inflammation, autoimmune diseases and host defense has led to the experimental targeting of the IL-17A pathway in animal models of diseases as well as in clinical trials in humans. These therapeutic agents include biological products that target IL-17A and IL-23, an upstream regulator of IL-17A production. IL-17A producing T helper cells (Th17 cells) are a distinct lineage from the Th1 and Th2 CD4+ lineages and have been suggested to represent a good drug target in certain inflammatory conditions. Targeting IL-17A has been proven to be a good approach as anti-IL-17A is FDA approved for the treatment of psoriasis in 2015. In host defense, IL-17A has been shown to be mostly beneficial against infection caused by extracellular bacteria and fungi. This review will overview the discovery of IL-17A, the receptors used by this cytokine and its role in mucosal immunity and inflammation. Twit Text FOAVip Interluekin-17A (IL17A) ????Gene http://www.kidney.de/pget.php?&tw=1&pmid=28122268 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28122268 #FOAvip English Wikipedia <ref>{{Cite pmid|28122268}}</ref> Interluekin-17A (IL17A) #MMPMID28122268 Chen K; Kolls JK Gene 2017[May]; 614 (ä): 8-14 PMID28122268show ga The discovery of the key roles of interleukin-17A (IL-17A) and IL-17A producing cells in inflammation, autoimmune diseases and host defense has led to the experimental targeting of the IL-17A pathway in animal models of diseases as well as in clinical trials in humans. These therapeutic agents include biological products that target IL-17A and IL-23, an upstream regulator of IL-17A production. IL-17A producing T helper cells (Th17 cells) are a distinct lineage from the Th1 and Th2 CD4+ lineages and have been suggested to represent a good drug target in certain inflammatory conditions. Targeting IL-17A has been proven to be a good approach as anti-IL-17A is FDA approved for the treatment of psoriasis in 2015. In host defense, IL-17A has been shown to be mostly beneficial against infection caused by extracellular bacteria and fungi. This review will overview the discovery of IL-17A, the receptors used by this cytokine and its role in mucosal immunity and inflammation. äInterluekin-17A (IL17A) (epmc).pdf DeepDyve Pubget Overpricing