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10.1101/gad.294108.116

http://scihub22266oqcxt.onion/10.1101/gad.294108.116
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C5393053!5393053!28381412
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suck abstract from ncbi


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pmid28381412      Genes+Dev 2017 ; 31 (6): 578-89
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  • The DDR at telomeres lacking intact shelterin does not require substantial chromatin decompaction #MMPMID28381412
  • Timashev LA; Babcock H; Zhuang X; de Lange T
  • Genes Dev 2017[Mar]; 31 (6): 578-89 PMID28381412show ga
  • In this study, Timashev et al. investigated the mechanism by which shelterin protects telomeres and performed superresolution imaging of telomeres in mouse cells after conditional deletion of TRF1, TRF2, or both, the latter of which results in the complete loss of shelterin. Their results indicate that the DNA damage response induced by shelterin removal does not require substantial telomere decompaction.
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