Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Genes+Dev 2017 ; 31 (6): 578-89 Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
The DDR at telomeres lacking intact shelterin does not require substantial chromatin decompaction #MMPMID28381412
Timashev LA; Babcock H; Zhuang X; de Lange T
Genes Dev 2017[Mar]; 31 (6): 578-89 PMID28381412show ga
In this study, Timashev et al. investigated the mechanism by which shelterin protects telomeres and performed superresolution imaging of telomeres in mouse cells after conditional deletion of TRF1, TRF2, or both, the latter of which results in the complete loss of shelterin. Their results indicate that the DNA damage response induced by shelterin removal does not require substantial telomere decompaction.