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10.1101/gad.294413.116

http://scihub22266oqcxt.onion/10.1101/gad.294413.116
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C5393050!5393050!28404629
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suck abstract from ncbi


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pmid28404629      Genes+Dev 2017 ; 31 (6): 537-52
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  • BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method #MMPMID28404629
  • Lim CS; Kang X; Mirabella V; Zhang H; Bu Q; Araki Y; Hoang ET; Wang S; Shen Y; Choi S; Kaang BK; Chang Q; Pang ZP; Huganir RL; Zhu JJ
  • Genes Dev 2017[Mar]; 31 (6): 537-52 PMID28404629show ga
  • Here, Lim et al. present a fast cost-effective lentivirus-based rapid gene replacement method to interrogate the physiopathology of BRaf and ?50 disease-linked BRaf mutants, including all CFC-linked mutants. This study establishes the first efficient procedure that permits large-scale functional analysis of human disease-linked mutations essential for precision medicine.
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