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10.18632/oncotarget.14474 http://scihub22266oqcxt.onion/10.18632/oncotarget.14474 C5392344!5392344!28060744     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (11): 18486-96 Nephropedia Template TP {{tp|p=28060744|t=2017. Targeting macrophage anti-tumor activity to suppress melanoma progression |pdf=|usr=}}{{28060744}} gab.com Text Targeting macrophage anti-tumor activity to suppress melanoma progression JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28060744 #FOAvip By phagocytosing cancer cells and their cellular debris, macrophages play a critical role in nonspecific defense (innate immunity) and, as antigen presenters, they help initiate specific defense mechanisms (adaptive immunity). Malignant melanoma is a lethal disease due to its aggressive capacity for metastasis and resistance to therapy. For decades, considerable effort has gone into development of an effective immunotherapy for treatment of metastatic melanoma. In this review, we focus on the anti-tumor activities of macrophages in melanoma and their potential as therapeutic targets in melanoma. Although macrophages can be re-educated through intercellular signaling to promote tumor survival owing to their plasticity, we expect that targeting the anti-tumor activity of macrophages remains a promising strategy for melanoma inhibition. The combination of tumoricidal macrophage activation and other treatments such as surgery, chemotherapy, and radiotherapy, may provide an effective and comprehensive anti-melanoma strategy. Twit Text FOAVip Targeting macrophage anti-tumor activity to suppress melanoma progression ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28060744 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28060744 #FOAvip English Wikipedia <ref>{{Cite pmid|28060744}}</ref> Targeting macrophage anti-tumor activity to suppress melanoma progression #MMPMID28060744 Wang H; Zhang L; Yang L; Liu C; Zhang Q; Zhang L Oncotarget 2017[Mar]; 8 (11): 18486-96 PMID28060744show ga By phagocytosing cancer cells and their cellular debris, macrophages play a critical role in nonspecific defense (innate immunity) and, as antigen presenters, they help initiate specific defense mechanisms (adaptive immunity). Malignant melanoma is a lethal disease due to its aggressive capacity for metastasis and resistance to therapy. For decades, considerable effort has gone into development of an effective immunotherapy for treatment of metastatic melanoma. In this review, we focus on the anti-tumor activities of macrophages in melanoma and their potential as therapeutic targets in melanoma. Although macrophages can be re-educated through intercellular signaling to promote tumor survival owing to their plasticity, we expect that targeting the anti-tumor activity of macrophages remains a promising strategy for melanoma inhibition. The combination of tumoricidal macrophage activation and other treatments such as surgery, chemotherapy, and radiotherapy, may provide an effective and comprehensive anti-melanoma strategy. äTargeting macrophage anti-tumor activity to suppress melanoma progress(epmc).pdf DeepDyve Pubget Overpricing