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2017 ; 28
(3
): 329-337
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Biomass Burning as a Source of Ambient Fine Particulate Air Pollution and Acute
Myocardial Infarction
#MMPMID28177951
Weichenthal S
; Kulka R
; Lavigne E
; van Rijswijk D
; Brauer M
; Villeneuve PJ
; Stieb D
; Joseph L
; Burnett RT
Epidemiology
2017[May]; 28
(3
): 329-337
PMID28177951
show ga
BACKGROUND: Biomass burning is an important source of ambient fine particulate
air pollution (PM2.5) in many regions of the world. METHODS: We conducted a
time-stratified case-crossover study of ambient PM2.5 and hospital admissions for
myocardial infarction (MI) in three regions of British Columbia, Canada. Daily
hospital admission data were collected between 2008 and 2015 and PM2.5 data were
collected from fixed site monitors. We used conditional logistic regression
models to estimate odds ratios (ORs) describing the association between PM2.5 and
the risk of hospital admission for MI. We used stratified analyses to evaluate
effect modification by biomass burning as a source of ambient PM2.5 using the
ratio of levoglucosan/PM2.5 mass concentrations. RESULTS: Each 5 µg/m increase in
3-day mean PM2.5 was associated with an increased risk of MI among elderly
subjects (?65 years; OR = 1.06, 95% CI: 1.03, 1.08); risk was not increased among
younger subjects. Among the elderly, the strongest association occurred during
colder periods (<6.44°C); when we stratified analyses by tertiles of monthly mean
biomass contributions to PM2.5 during cold periods, ORs of 1.19 (95% CI: 1.04,
1.36), 1.08 (95% CI: 1.06, 1.09), and 1.04 (95% CI: 1.03, 1.06) were observed in
the upper, middle, and lower tertiles (Ptrend = 0.003), respectively. CONCLUSION:
Short-term changes in ambient PM2.5 were associated with an increased risk of MI
among elderly subjects. During cold periods, increased biomass burning
contributions to PM2.5 may modify its association with MI.
|*Biomass
[MESH]
|*Particulate Matter/analysis/chemistry
[MESH]
|Aged
[MESH]
|Air Pollution/analysis/*statistics & numerical data
[MESH]