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10.1038/srep46348 http://scihub22266oqcxt.onion/10.1038/srep46348 C5389357!5389357 !28402334     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28402334 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Rep 2017 ; 7 (ä): 46348 Nephropedia Template TP {{tp|p=28402334 |t=2017. Characterization of c-Maf(+)Foxp3(-) Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells |pdf=|usr=}}{{28402334 }} gab.com Text Characterization of c-Maf(+)Foxp3(-) Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28402334 #FOAvip The role of B cells in the development of CD4(+) regulatory T cells has been emphasized recently. Our previous studies have demonstrated that the antigen-presenting splenic B cells converted naïve CD4(+)CD25(-) T cells into CD4(+)CD25(+)Foxp3(-) T cells without additional cytokines or chemicals with regulatory activity and that referred to as Treg-of-B cells. The present study further showed that Treg-of-B cells increased the IL-10-producing population, and the expression of c-Maf, inducible T-cell co-stimulator (ICOS) as well as cytotoxic T-lymphocyte-associated protein 4 (CTLA4) after repeated stimulation of B cells in a cell-cell contact-dependent manner. Long-term cultured Treg-of-B cells exerted IL-10 and CTLA4-mediated antigen-specific suppressive activity; moreover, the single antigen-specific Treg-of-B cells inhibited in a non-antigen-specific fashion. In conclusion, these results suggest that repeated stimulation of B cells induced IL-10-producing CD4(+)Foxp3(-) regulatory T cells in a contact-dependent manner and these Treg-of-B cells possess IL-10 and CTLA4-dependent suppressive function. Twit Text FOAVip Characterization of c-Maf(+)Foxp3(-) Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28402334 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28402334 #FOAvip English Wikipedia <ref>{{Cite pmid|28402334 }}</ref> Characterization of c-Maf(+)Foxp3(-) Regulatory T Cells Induced by Repeated Stimulation of Antigen-Presenting B Cells #MMPMID28402334 Chien CH ; Yu HC ; Chen SY ; Chiang BL Sci Rep 2017[Apr]; 7 (ä): 46348 PMID28402334 show ga The role of B cells in the development of CD4(+) regulatory T cells has been emphasized recently. Our previous studies have demonstrated that the antigen-presenting splenic B cells converted naïve CD4(+)CD25(-) T cells into CD4(+)CD25(+)Foxp3(-) T cells without additional cytokines or chemicals with regulatory activity and that referred to as Treg-of-B cells. The present study further showed that Treg-of-B cells increased the IL-10-producing population, and the expression of c-Maf, inducible T-cell co-stimulator (ICOS) as well as cytotoxic T-lymphocyte-associated protein 4 (CTLA4) after repeated stimulation of B cells in a cell-cell contact-dependent manner. Long-term cultured Treg-of-B cells exerted IL-10 and CTLA4-mediated antigen-specific suppressive activity; moreover, the single antigen-specific Treg-of-B cells inhibited in a non-antigen-specific fashion. In conclusion, these results suggest that repeated stimulation of B cells induced IL-10-producing CD4(+)Foxp3(-) regulatory T cells in a contact-dependent manner and these Treg-of-B cells possess IL-10 and CTLA4-dependent suppressive function. |Animals [MESH] |Antigen Presentation/*immunology [MESH] |B-Lymphocytes/*immunology/*metabolism [MESH] |Biomarkers [MESH] |CD4-Positive T-Lymphocytes/immunology/metabolism [MESH] |Cell Communication/immunology [MESH] |Cytokines/metabolism [MESH] |Female [MESH] |Forkhead Transcription Factors/metabolism [MESH] |Mice [MESH] |Models, Biological [MESH] |Proto-Oncogene Proteins c-maf/metabolism [MESH] |T-Lymphocyte Subsets/immunology/metabolism [MESH]Characterization of c-Maf(+)Foxp3(-) Regulatory T Cells Induced by Rep(epmc).pdf DeepDyve Pubget Overpricing