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10.3233/JHD-160222 http://scihub22266oqcxt.onion/10.3233/JHD-160222 C5389024!5389024!28128770     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Huntingtons+Dis ä ; 6 (1): 19-31 Nephropedia Template TP {{tp|p=28128770|t=ä. Modern Genome Editing Technologies in Huntington?s Disease Research |pdf=|usr=}}{{28128770}} gab.com Text Modern Genome Editing Technologies in Huntington s Disease Research JO: J Huntingtons Dis http://www.kidney.de/pget.php?&tw=1&pmid=28128770 #FOAvip The development of new revolutionary technologies for directed gene editing has made it possible to thoroughly model and study NgAgo human diseases at the cellular and molecular levels. Gene editing tools like ZFN, TALEN, CRISPR-based systems, NgAgo and SGN can introduce different modifications. In gene sequences and regulate gene expression in different types of cells including induced pluripotent stem cells (iPSCs). These tools can be successfully used for Huntington?s disease (HD) modeling, for example, to generate isogenic cell lines bearing different numbers of CAG repeats or to correct the mutation causing the disease. This review presents common genome editing technologies and summarizes the progress made in using them in HD and other hereditary diseases. Furthermore, we will discuss prospects and limitations of genome editing in understanding HD pathology. Twit Text FOAVip Modern Genome Editing Technologies in Huntington s Disease Research ????J Huntingtons Dis http://www.kidney.de/pget.php?&tw=1&pmid=28128770 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28128770 #FOAvip English Wikipedia <ref>{{Cite pmid|28128770}}</ref> Modern Genome Editing Technologies in Huntington?s Disease Research #MMPMID28128770 Malankhanova TB; Malakhova AA; Medvedev SP; Zakian SM J Huntingtons Dis ä[]; 6 (1): 19-31 PMID28128770show ga The development of new revolutionary technologies for directed gene editing has made it possible to thoroughly model and study NgAgo human diseases at the cellular and molecular levels. Gene editing tools like ZFN, TALEN, CRISPR-based systems, NgAgo and SGN can introduce different modifications. In gene sequences and regulate gene expression in different types of cells including induced pluripotent stem cells (iPSCs). These tools can be successfully used for Huntington?s disease (HD) modeling, for example, to generate isogenic cell lines bearing different numbers of CAG repeats or to correct the mutation causing the disease. This review presents common genome editing technologies and summarizes the progress made in using them in HD and other hereditary diseases. Furthermore, we will discuss prospects and limitations of genome editing in understanding HD pathology. äModern Genome Editing Technologies in Huntington?s Disease Research (epmc).pdf DeepDyve Pubget Overpricing