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10.1016/j.neuroimage.2017.02.008 http://scihub22266oqcxt.onion/10.1016/j.neuroimage.2017.02.008 C5387158!5387158!28179164     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Neuroimage 2017 ; 149 (ä): 415-23 Nephropedia Template TP {{tp|p=28179164|t=2017. Metacognitive ability correlates with hippocampal and prefrontal microstructure |pdf=|usr=}}{{28179164}} gab.com Text Metacognitive ability correlates with hippocampal and prefrontal microstructure JO: Neuroimage http://www.kidney.de/pget.php?&tw=1&pmid=28179164 #FOAvip The ability to introspectively evaluate our experiences to form accurate metacognitive beliefs, or insight, is an essential component of decision-making. Previous research suggests individuals vary substantially in their level of insight, and that this variation is related to brain volume and function, particularly in the anterior prefrontal cortex (aPFC). However, the neurobiological mechanisms underlying these effects are unclear, as qualitative, macroscopic measures such as brain volume can be related to a variety of microstructural features. Here we leverage a high-resolution (800 µm isotropic) multi-parameter mapping technique in 48 healthy individuals to delineate quantitative markers of in vivo histological features underlying metacognitive ability. Specifically, we examined how neuroimaging markers of local grey matter myelination and iron content relate to insight as measured by a signal-theoretic model of subjective confidence. Our results revealed a pattern of microstructural correlates of perceptual metacognition in the aPFC, precuneus, hippocampus, and visual cortices. In particular, we extend previous volumetric findings to show that right aPFC myeloarchitecture positively relates to metacognitive insight. In contrast, decreased myelination in the left hippocampus correlated with better metacognitive insight. These results highlight the ability of quantitative neuroimaging to reveal novel brain-behaviour correlates and may motivate future research on their environmental and developmental underpinnings. Twit Text FOAVip Metacognitive ability correlates with hippocampal and prefrontal microstructure ????Neuroimage http://www.kidney.de/pget.php?&tw=1&pmid=28179164 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28179164 #FOAvip English Wikipedia <ref>{{Cite pmid|28179164}}</ref> Metacognitive ability correlates with hippocampal and prefrontal microstructure #MMPMID28179164 Allen M; Glen JC; Müllensiefen D; Schwarzkopf DS; Fardo F; Frank D; Callaghan MF; Rees G Neuroimage 2017[Apr]; 149 (ä): 415-23 PMID28179164show ga The ability to introspectively evaluate our experiences to form accurate metacognitive beliefs, or insight, is an essential component of decision-making. Previous research suggests individuals vary substantially in their level of insight, and that this variation is related to brain volume and function, particularly in the anterior prefrontal cortex (aPFC). However, the neurobiological mechanisms underlying these effects are unclear, as qualitative, macroscopic measures such as brain volume can be related to a variety of microstructural features. Here we leverage a high-resolution (800 µm isotropic) multi-parameter mapping technique in 48 healthy individuals to delineate quantitative markers of in vivo histological features underlying metacognitive ability. Specifically, we examined how neuroimaging markers of local grey matter myelination and iron content relate to insight as measured by a signal-theoretic model of subjective confidence. Our results revealed a pattern of microstructural correlates of perceptual metacognition in the aPFC, precuneus, hippocampus, and visual cortices. In particular, we extend previous volumetric findings to show that right aPFC myeloarchitecture positively relates to metacognitive insight. In contrast, decreased myelination in the left hippocampus correlated with better metacognitive insight. These results highlight the ability of quantitative neuroimaging to reveal novel brain-behaviour correlates and may motivate future research on their environmental and developmental underpinnings. äMetacognitive ability correlates with hippocampal and prefrontal micro(epmc).pdf DeepDyve Pubget Overpricing