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10.18632/oncotarget.15361 http://scihub22266oqcxt.onion/10.18632/oncotarget.15361 C5386706!5386706!28223537     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (12): 19566-76 Nephropedia Template TP {{tp|p=28223537|t=2017. Reduced E-cadherin facilitates renal cell carcinoma progression by WNT/?-catenin signaling activation |pdf=|usr=}}{{28223537}} gab.com Text Reduced E-cadherin facilitates renal cell carcinoma progression by WNT/ -catenin signaling activation JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28223537 #FOAvip Reduced expression of E-cadherin was observed in renal cell carcinoma (RCC). However, its potential clinical value and correlation with WNT/?-catenin signaling in RCC progression was still unclear. Immunohistochemical staining was performed in RCC tissue microarray to examine the expression status and prognosis value of E-cadherin and ?-catenin. The potential role of E-cadherin in ?-catenin translocation was analyzed with immunobloting assays. A significant negative correlation was observed between E-cadherin and ?-catenin expression in RCC tissues. E-cadherin inhibits ?-catenin translocation from membrane to cytoplasm in RCC tissues, which was an important step for WNT/?-catenin signaling. Reduced E-cadherin expression was associated with poor prognosis. More importantly, E-cadherin-/?-catenin+ was an independent detrimental factor for survival estimation of RCC patients. Reduced E-cadherin expression in RCC promoted cancer progression via WNT/?-catenin signaling pathway activation. E-cadherin/?-catenin provides a valuable prognosis marker for RCC, which may be an effective target for RCC therapy. Twit Text FOAVip Reduced E-cadherin facilitates renal cell carcinoma progression by WNT/ -catenin signaling activation ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28223537 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28223537 #FOAvip English Wikipedia <ref>{{Cite pmid|28223537}}</ref> Reduced E-cadherin facilitates renal cell carcinoma progression by WNT/?-catenin signaling activation #MMPMID28223537 Zhang X; Yang M; Shi H; Hu J; Wang Y; Sun Z; Xu S Oncotarget 2017[Mar]; 8 (12): 19566-76 PMID28223537show ga Reduced expression of E-cadherin was observed in renal cell carcinoma (RCC). However, its potential clinical value and correlation with WNT/?-catenin signaling in RCC progression was still unclear. Immunohistochemical staining was performed in RCC tissue microarray to examine the expression status and prognosis value of E-cadherin and ?-catenin. The potential role of E-cadherin in ?-catenin translocation was analyzed with immunobloting assays. A significant negative correlation was observed between E-cadherin and ?-catenin expression in RCC tissues. E-cadherin inhibits ?-catenin translocation from membrane to cytoplasm in RCC tissues, which was an important step for WNT/?-catenin signaling. Reduced E-cadherin expression was associated with poor prognosis. More importantly, E-cadherin-/?-catenin+ was an independent detrimental factor for survival estimation of RCC patients. Reduced E-cadherin expression in RCC promoted cancer progression via WNT/?-catenin signaling pathway activation. E-cadherin/?-catenin provides a valuable prognosis marker for RCC, which may be an effective target for RCC therapy. äReduced E-cadherin facilitates renal cell carcinoma progression by WNT(epmc).pdf DeepDyve Pubget Overpricing