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2017 ; 9
(3
): e1086
Nephropedia Template TP
gab.com Text
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English Wikipedia
An Unfortunate Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal
Gammopathy, and Skin Change (POEMS)
#MMPMID28405536
Afridi F
; Otoya J
; Bunting SF
; Chaaya G
Cureus
2017[Mar]; 9
(3
): e1086
PMID28405536
show ga
POEMS syndrome is an acronym for polyneuropathy, organomegaly, endocrinopathy,
monoclonal gammopathy and skin changes, which is a rare paraneoplastic disease of
monoclonal plasma cells. A mandatory criterion to diagnose POEMS syndrome is the
presence of a monoclonal plasma cell dyscrasia in which plasma cell leukemia is
the most aggressive form. Early identification of the features of the POEMS
syndrome is critical for patients to identify an underlying plasma cell
dyscrasias and to reduce the morbidity and mortality of the disease by providing
early therapy. We present a case of a 64-year-old male who presented with
non-specific symptoms and was found to have primary plasma cell leukemia, which
was part of his unfortunate POEMS syndrome.