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10.1080/15384101.2017.1281486 http://scihub22266oqcxt.onion/10.1080/15384101.2017.1281486 C5384587!5384587!28103135     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Cycle 2017 ; 16 (6): 533-5 Nephropedia Template TP {{tp|p=28103135|t=2017. Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis |pdf=|usr=}}{{28103135}} gab.com Text Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis JO: Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=28103135 #FOAvip The tumor microenvironment is critical for metastasis to occur. Subcutaneous xenografts of tumors in immunodeficient mice are usually encapsulated and rarely metastasize as opposed to orthotopic tumors which metastasize if the original tumor was metastatic. In the present report, we were able to reconstitute a metastatic tumor microenvironment by subcutaneously co-transplanting a human cervical cancer cell line and human cervical cancer-associated fibroblasts (CAFs), in athymic mice, which resulted in lymph node metastasis in 40% of the animals. In contrast, no metastasis occurred from the cervical cancer without CAFs. These results suggest that CAFs can overcome an anti-metastatic tumor environment and are a potential target to prevent metastasis. Twit Text FOAVip Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis ????Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=28103135 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28103135 #FOAvip English Wikipedia <ref>{{Cite pmid|28103135}}</ref> Reconstitution of a metastatic-resistant tumor microenvironment with cancer-associated fibroblasts enables metastasis #MMPMID28103135 Murata T; Mekada E; Hoffman RM Cell Cycle 2017[]; 16 (6): 533-5 PMID28103135show ga The tumor microenvironment is critical for metastasis to occur. Subcutaneous xenografts of tumors in immunodeficient mice are usually encapsulated and rarely metastasize as opposed to orthotopic tumors which metastasize if the original tumor was metastatic. In the present report, we were able to reconstitute a metastatic tumor microenvironment by subcutaneously co-transplanting a human cervical cancer cell line and human cervical cancer-associated fibroblasts (CAFs), in athymic mice, which resulted in lymph node metastasis in 40% of the animals. In contrast, no metastasis occurred from the cervical cancer without CAFs. These results suggest that CAFs can overcome an anti-metastatic tumor environment and are a potential target to prevent metastasis. äReconstitution of a metastatic-resistant tumor microenvironment with c(epmc).pdf DeepDyve Pubget Overpricing