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10.1080/15384101.2017.1282585 http://scihub22266oqcxt.onion/10.1080/15384101.2017.1282585 C5384577!5384577!28118071     free     free     free       Cell+Cycle 2017 ; 16 (6): 515-21 Nephropedia Template TP {{tp|p=28118071|t=2017. The role of WRNIP1 in genome maintenance |pdf=|usr=}}{{28118071}} gab.com Text The role of WRNIP1 in genome maintenance JO: Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=28118071 #FOAvip WRNIP1 interacts with WRN helicase, which is defective in the premature aging disease Werner syndrome. WRNIP1 belongs to the AAA+ ATPase family and is conserved from Escherichia coli to human. The protein contains an ubiquitin-binding zinc finger (UBZ) domain at the N terminus and an ATPase domain in the middle region. In addition to WRN, WRNIP1 interacts with proteins involved in multiple cellular pathways, including RAD18, monoubiquitylated PCNA, DNA polymerase ?, RAD51, and ATMIN. Mgs1, the yeast homolog of WRNIP1, may act downstream of ubiquitylation of PCNA to mobilize DNA polymerase ?. By contrast, the functions of WRNIP1 in higher eukaryotic cells remain obscure, although data regarding the roles of WRNIP1 in DNA transactions have emerged recently. Here, we first describe the functions of Mgs1 in DNA transaction. We then describe various features of WRNIP1 and discuss its possible roles based on recent studies of the function of WRNIP1. Twit Text FOAVip The role of WRNIP1 in genome maintenance ????Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=28118071 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28118071 #FOAvip English Wikipedia <ref>{{Cite pmid|28118071}}</ref> The role of WRNIP1 in genome maintenance #MMPMID28118071 Yoshimura A; Seki M; Enomoto T Cell Cycle 2017[]; 16 (6): 515-21 PMID28118071show ga WRNIP1 interacts with WRN helicase, which is defective in the premature aging disease Werner syndrome. WRNIP1 belongs to the AAA+ ATPase family and is conserved from Escherichia coli to human. The protein contains an ubiquitin-binding zinc finger (UBZ) domain at the N terminus and an ATPase domain in the middle region. In addition to WRN, WRNIP1 interacts with proteins involved in multiple cellular pathways, including RAD18, monoubiquitylated PCNA, DNA polymerase ?, RAD51, and ATMIN. Mgs1, the yeast homolog of WRNIP1, may act downstream of ubiquitylation of PCNA to mobilize DNA polymerase ?. By contrast, the functions of WRNIP1 in higher eukaryotic cells remain obscure, although data regarding the roles of WRNIP1 in DNA transactions have emerged recently. Here, we first describe the functions of Mgs1 in DNA transaction. We then describe various features of WRNIP1 and discuss its possible roles based on recent studies of the function of WRNIP1. äThe role of WRNIP1 in genome maintenance (epmc).pdf DeepDyve Pubget Overpricing