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2017 ; 60
(5
): 284-295
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Understanding the formidable nail barrier: A review of the nail microstructure,
composition and diseases
#MMPMID28098391
Baswan S
; Kasting GB
; Li SK
; Wickett R
; Adams B
; Eurich S
; Schamper R
Mycoses
2017[May]; 60
(5
): 284-295
PMID28098391
show ga
The topical treatment of nail fungal infections has been a focal point of nail
research in the past few decades as it offers a much safer and focused
alternative to conventional oral therapy. Although the current focus remains on
exploring the ways of enhancing permeation through the formidable nail barrier,
the understanding of the nail microstructure and composition is far from
complete. This article reviews our current understanding of the nail
microstructure, composition and diseases. A few of the parameters affecting the
nail permeability and potential causes of the recurrence of fungal nail infection
are also discussed.
|Administration, Topical
[MESH]
|Antifungal Agents/administration & dosage/*pharmacokinetics/therapeutic use
[MESH]