Mitochondria: Masters of Epigenetics #MMPMID27203109
Tatar M; Sedivy JM
Cell 2016[May]; 165 (5): 1052-4 PMID27203109show ga
Accumulating evidence argues that aging exerts a profound influence on epigenetics, and vice versa. A pair of studies by Merkwirth et al. and Tian et al. now provide insights on how mitochondrial stress experienced by C. elegans larvae propagates a specific and persistent epigenetic response that protects adult cells and extends lifespan.