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2017 ; 12
(4
): 677-686
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IgA Nephropathy
#MMPMID28159829
Rodrigues JC
; Haas M
; Reich HN
Clin J Am Soc Nephrol
2017[Apr]; 12
(4
): 677-686
PMID28159829
show ga
IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent
international collaborative efforts have led to important discoveries that have
improved our understanding of some of the key steps involved in the
immunopathogenesis of IgAN. Furthermore, establishment of multicenter networks
has contributed to rigorous design and execution of clinical trials that have
provided important insights regarding immunotherapy in IgAN. In this article, we
review emerging developments in clinical and translational IgAN research and
describe how these novel findings will influence future strategies to improve the
outcome of patients with IgAN.