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2017 ; 49
(1
): 31-37
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English Wikipedia
Impact of Intervention by an Antimicrobial Stewardship Team on Conversion from
Intravenous to Oral Fluoroquinolones
#MMPMID28332344
Park SM
; Kim HS
; Jeong YM
; Lee JH
; Lee E
; Lee E
; Song KH
; Kim HB
; Kim ES
Infect Chemother
2017[Mar]; 49
(1
): 31-37
PMID28332344
show ga
BACKGROUND: Early conversion from intravenous to oral antibiotics plays an
important role in lowering the risk of catheter-associated infections, reducing
the workload of nurses, decreasing direct and indirect costs, and shortening
hospital stays. In August 2015, an antimicrobial stewardship program (ASP) was
implemented to facilitate conversion from intravenous to oral administration of
fluoroquinolones in our institute. This study evaluated the clinical and economic
impact of the intervention. MATERIALS AND METHODS: Data were retrospectively
collected by reviewing electronic medical records. All hospitalized patients aged
18 and older who met the study inclusion criteria for the conversion were
included between August and November 2015. We computed the physicians' adherence
rate to the ASP recommendations. We also measured the total use of
fluoroquinolones, length of hospital stay, and medication costs. RESULTS: During
4 months, 129 cases were enrolled in the study. The adherence rate was 79.8%. The
average total prescription volume of intravenous fluoroquinolones, the length of
hospital stay, and the total cost of the fluoroquinolones statistically
significantly decreased in the intervention-adherent group. CONCLUSION:
Intervention to facilitate conversion from intravenous to oral administration has
reduced excess use of intravenous fluoroquinolones and length of hospital stay.
With these findings, further implementations of the ASP extending to other
antibiotics may be warranted.