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10.1016/j.tips.2017.01.008 http://scihub22266oqcxt.onion/10.1016/j.tips.2017.01.008 C5381697!5381697!28214012     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Pharmacol+Sci 2017 ; 38 (4): 322-38 Nephropedia Template TP {{tp|p=28214012|t=2017. The Endothelium Solves Problems That Endothelial Cells Do Not Know Exist |pdf=|usr=}}{{28214012}} gab.com Text The Endothelium Solves Problems That Endothelial Cells Do Not Know Exist JO: Trends Pharmacol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28214012 #FOAvip The endothelium is the single layer of cells that lines the entire cardiovascular system and regulates vascular tone and blood?tissue exchange, recruits blood cells, modulates blood clotting, and determines the formation of new blood vessels. To control each function, the endothelium uses a remarkable sensory capability to continuously monitor vanishingly small changes in the concentrations of many simultaneously arriving extracellular activators that each provides cues to the physiological state. Here we suggest that the extraordinary sensory capabilities of the endothelium do not come from single cells but from the combined activity of a large number of endothelial cells. Each cell has a limited, but distinctive, sensory capacity and shares information with neighbours so that sensing is distributed among cells. Communication of information among connected cells provides system-level sensing substantially greater than the capabilities of any single cell and, as a collective, the endothelium solves sensory problems too complex for any single cell. Twit Text FOAVip The Endothelium Solves Problems That Endothelial Cells Do Not Know Exist ????Trends Pharmacol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28214012 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28214012 #FOAvip English Wikipedia <ref>{{Cite pmid|28214012}}</ref> The Endothelium Solves Problems That Endothelial Cells Do Not Know Exist #MMPMID28214012 McCarron JG; Lee MD; Wilson C Trends Pharmacol Sci 2017[Apr]; 38 (4): 322-38 PMID28214012show ga The endothelium is the single layer of cells that lines the entire cardiovascular system and regulates vascular tone and blood?tissue exchange, recruits blood cells, modulates blood clotting, and determines the formation of new blood vessels. To control each function, the endothelium uses a remarkable sensory capability to continuously monitor vanishingly small changes in the concentrations of many simultaneously arriving extracellular activators that each provides cues to the physiological state. Here we suggest that the extraordinary sensory capabilities of the endothelium do not come from single cells but from the combined activity of a large number of endothelial cells. Each cell has a limited, but distinctive, sensory capacity and shares information with neighbours so that sensing is distributed among cells. Communication of information among connected cells provides system-level sensing substantially greater than the capabilities of any single cell and, as a collective, the endothelium solves sensory problems too complex for any single cell. äThe Endothelium Solves Problems That Endothelial Cells Do Not Know Exi(epmc).pdf DeepDyve Pubget Overpricing