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2017 ; 9
(1
): 7-19
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Comparative Phylogenomic Assessment of Mitochondrial Introgression among Several
Species of Chipmunks (Tamias)
#MMPMID28172670
Sarver BA
; Demboski JR
; Good JM
; Forshee N
; Hunter SS
; Sullivan J
Genome Biol Evol
2017[Jan]; 9
(1
): 7-19
PMID28172670
show ga
Many species are not completely reproductively isolated, resulting in
hybridization and genetic introgression. Organellar genomes, such as those
derived from mitochondria (mtDNA) and chloroplasts, introgress frequently in
natural systems; however, the forces shaping patterns of introgression are not
always clear. Here, we investigate extensive mtDNA introgression in western
chipmunks, focusing on species in the Tamias quadrivittatus group from the
central and southern Rocky Mountains. Specifically, we investigate the role of
selection in driving patterns of introgression. We sequenced 51 mtDNA genomes
from six species and combine these sequences with other published genomic data to
yield annotated mitochondrial reference genomes for nine species of chipmunks.
Genomic characterization was performed using a series of molecular evolutionary
and phylogenetic analyses to test protein-coding genes for positive selection. We
fit a series of maximum likelihood models using a model-averaging approach,
assessed deviations from neutral expectations, and performed additional tests to
search for codons under the influence of selection. We found no evidence for
positive selection among these genomes, suggesting that selection has not been
the driving force of introgression in these species. Thus, extensive mtDNA
introgression among several species of chipmunks likely reflects genetic drift of
introgressed alleles in historically fluctuating populations.