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10.1093/ckj/sfw110

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suck abstract from ncbi


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pmid28396739      Clin+Kidney+J 2017 ; 10 (2): 229-32
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  • Nephrotic syndrome due to minimal change disease secondary to spider bite: clinico-pathological case of a non-described complication of latrodectism #MMPMID28396739
  • Méndez GP; Enos D; Moreira JL; Alvaredo F; Oddó D
  • Clin Kidney J 2017[Apr]; 10 (2): 229-32 PMID28396739show ga
  • The patient was an 18-year-old man who developed nephrotic syndrome after a ?wheat spider? bite (Latrodectus mactans). Due to this atypical manifestation of latrodectism, a renal biopsy was performed showing minimal change disease. The nephrotic syndrome subsided after 1 week without specific treatment. This self-limited evolution suggests that the mechanism of podocyte damage was temporary and potentially mediated by a secondary mechanism of hypersensitivity or direct effect of the ?-latrotoxin. The patient did not show signs of relapse in subsequent checkup. This is the first reported case of nephrotic syndrome due to a minimal change lesion secondary to latrodectism.
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