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2017 ; 10
(1
): 149
Nephropedia Template TP
gab.com Text
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Pattern of acute organophosphorus poisoning at University of Gondar Teaching
Hospital, Northwest Ethiopia
#MMPMID28376842
Adinew GM
; Asrie AB
; Birru EM
BMC Res Notes
2017[Apr]; 10
(1
): 149
PMID28376842
show ga
BACKGROUND: Despite the apparent benefits of organophosphate compounds (OPCs)
acute organophosphate (OP) pesticide poison is an increasing problem worldwide.
In a country like Ethiopia, where agriculture is a major component of the
economy, these compounds are readily available to the general public. There is
paucity of evidence from Ethiopia showing the pattern of organophosphate
poisoning (OPP) in healthcare facilities. The objective of this study was to
evaluate retrospectively the pattern of acute OPP at the University of Gondar
Teaching Hospital in northwest Ethiopia, during September 2010 through December
2014 was conducted. Data was collected through chart review of patients who were
admitted due to poisoning. Data was analysed using SPSS 20. RESULTS:
Organophosphate poisoning in University of Gondar teaching hospital accounts for
about 38.46% of all emergency room admissions for poisoning. Out of the 90 cases
studied 60% (54) were women, with male to female ratio of 1:1.5. The mean age of
the patients was 25.5 with a standard deviation of 9.45. 56.7% of the cases
studies lived in an urban environment compared to 43.3% who lived rurally. In the
vast majority of patients, 90% (81) patients had ingested OP as an act of
suicide. Regarding the route of exposure, oral ingestion was most common in
suicidal cases (88.9%). The elapsed time between the time of poison ingestion and
the start of the treatment, ranged from 13 min to 1 day. Health care
professionals' useds decontamination methods such as gastric lavage and activated
charcoal (45.6%) and 36.7% use atropine for OPP treatment. The mean hospital stay
was 0.74 days. In the present study family problems were a leading cause of
suicides and accounted for 45.8% of all cases. CONCLUSION: As a developing nation
who economy relies heavily on agriculture, Ethiopia continues to have OP
compounds remain a common cause of acute poisonings. This is particularly
concerning for younger generation who have high rates of OPP and whose numbers
continue to raise. This data suggests that it is essential to strengthen
Ethiopians regulatory policy concerning the availability of OPCs. Additionally,
it will be important to design an appropriate health education program for the
prevention of both suicidal and accidental OPPs for the benefit of the public at
large.
|Acute Disease
[MESH]
|Adolescent
[MESH]
|Adult
[MESH]
|Atropine/therapeutic use
[MESH]
|Bronchodilator Agents/therapeutic use
[MESH]
|Charcoal/therapeutic use
[MESH]
|Child
[MESH]
|Emergency Service, Hospital/*statistics & numerical data
[MESH]
|Ethiopia
[MESH]
|Female
[MESH]
|Gastric Lavage/methods
[MESH]
|Hospitals, Teaching/*statistics & numerical data
[MESH]
|Humans
[MESH]
|Male
[MESH]
|Middle Aged
[MESH]
|Organophosphate Poisoning/*therapy
[MESH]
|Retrospective Studies
[MESH]
|Risk Factors
[MESH]
|Rural Population/statistics & numerical data
[MESH]
|Suicide, Attempted/statistics & numerical data
[MESH]
|Surveys and Questionnaires
[MESH]
|Urban Population/statistics & numerical data
[MESH]