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10.1038/srep46042 http://scihub22266oqcxt.onion/10.1038/srep46042 C5380965!5380965!28378770     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28378770|t=2017. Unraveling the role of Calcium ions in the mechanical properties of individual collagen fibrils |pdf=|usr=}}{{28378770}} gab.com Text Unraveling the role of Calcium ions in the mechanical properties of individual collagen fibrils JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28378770 #FOAvip Collagen, the dominating material in the extracellular matrix, provides the strength, elasticity and mechanical stability to the organisms. The mechanical property of collagen is mainly dominated by its surrounding environments. However, the variation and origin of the mechanics of collagen fibril under different concentrations of calcium ions (?Ca) remains unknown. By using the atomic force microscopy based nanoindentation, the mechanics and structure of individual type II collagen fibril were first investigated under different ?Ca in this study. The results demonstrate that both of the mechanical and structural properties of the collagen fibril show a prominent dependence on ?Ca. The mechanism of ?Ca-dependence of the collagen fibril was attributed to the chelation between collagen molecules and the calcium ions. Given the role of calcium in the pathology of osteoarthritis, the current study may cast new light on the understanding of osteoarthritis and other soft tissue hardening related diseases in the future. Twit Text FOAVip Unraveling the role of Calcium ions in the mechanical properties of individual collagen fibrils ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28378770 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28378770 #FOAvip English Wikipedia <ref>{{Cite pmid|28378770}}</ref> Unraveling the role of Calcium ions in the mechanical properties of individual collagen fibrils #MMPMID28378770 Pang X; Lin L; Tang B Sci Rep 2017[]; 7 (ä): ä PMID28378770show ga Collagen, the dominating material in the extracellular matrix, provides the strength, elasticity and mechanical stability to the organisms. The mechanical property of collagen is mainly dominated by its surrounding environments. However, the variation and origin of the mechanics of collagen fibril under different concentrations of calcium ions (?Ca) remains unknown. By using the atomic force microscopy based nanoindentation, the mechanics and structure of individual type II collagen fibril were first investigated under different ?Ca in this study. The results demonstrate that both of the mechanical and structural properties of the collagen fibril show a prominent dependence on ?Ca. The mechanism of ?Ca-dependence of the collagen fibril was attributed to the chelation between collagen molecules and the calcium ions. Given the role of calcium in the pathology of osteoarthritis, the current study may cast new light on the understanding of osteoarthritis and other soft tissue hardening related diseases in the future. äUnraveling the role of Calcium ions in the mechanical properties of in(epmc).pdf DeepDyve Pubget Overpricing