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10.1038/srep46024

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suck abstract from ncbi


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pmid28378772
      Sci+Rep 2017 ; 7 (ä): 46024
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  • Activation of perineuronal net-expressing excitatory neurons during associative memory encoding and retrieval #MMPMID28378772
  • Morikawa S ; Ikegaya Y ; Narita M ; Tamura H
  • Sci Rep 2017[Apr]; 7 (ä): 46024 PMID28378772 show ga
  • Perineuronal nets (PNNs), proteoglycan-rich extracellular matrix structures, are thought to be expressed around inhibitory neurons and contribute to critical periods of brain function and synaptic plasticity. However, in some specific brain regions such as the amygdala, PNNs were predominantly expressed around excitatory neurons. These neurons were recruited during auditory fear conditioning and memory retrieval. Indeed, the activation of PNN-expressing excitatory neurons predicted cognitive performance.
  • |*Memory [MESH]
  • |*Mental Recall [MESH]
  • |Aggrecans/metabolism [MESH]
  • |Amygdala/metabolism [MESH]
  • |Animals [MESH]
  • |Cell Aggregation [MESH]
  • |Fear [MESH]
  • |Male [MESH]
  • |Mice, Inbred C57BL [MESH]
  • |Nerve Net/*physiology [MESH]
  • |Neurons/*metabolism [MESH]
  • |Parvalbumins/metabolism [MESH]


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