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10.1084/jem.20161382 http://scihub22266oqcxt.onion/10.1084/jem.20161382 C5379978!5379978 !28351984     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28351984 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Exp+Med 2017 ; 214 (4 ): 1111-1128 Nephropedia Template TP {{tp|p=28351984 |t=2017. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity |pdf=|usr=}}{{28351984 }} gab.com Text Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity JO: J Exp Med http://www.kidney.de/pget.php?&tw=1&pmid=28351984 #FOAvip The phagocyte respiratory burst is crucial for innate immunity. The transfer of electrons to oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22phox subunits. Deficiency of either subunit leads to severe immunodeficiency. We describe Eros (essential for reactive oxygen species), a protein encoded by the previously undefined mouse gene bc017643, and show that it is essential for host defense via the phagocyte NAPDH oxidase. Eros is required for expression of the NADPH oxidase components, gp91phox and p22phox Consequently, Eros-deficient mice quickly succumb to infection. Eros also contributes to the formation of neutrophil extracellular traps (NETS) and impacts on the immune response to melanoma metastases. Eros is an ortholog of the plant protein Ycf4, which is necessary for expression of proteins of the photosynthetic photosystem 1 complex, itself also an NADPH oxio-reductase. We thus describe the key role of the previously uncharacterized protein Eros in host defense. Twit Text FOAVip Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity ????J Exp Med http://www.kidney.de/pget.php?&tw=1&pmid=28351984 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28351984 #FOAvip English Wikipedia <ref>{{Cite pmid|28351984 }}</ref> Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity #MMPMID28351984 Thomas DC ; Clare S ; Sowerby JM ; Pardo M ; Juss JK ; Goulding DA ; van der Weyden L ; Storisteanu D ; Prakash A ; Espéli M ; Flint S ; Lee JC ; Hoenderdos K ; Kane L ; Harcourt K ; Mukhopadhyay S ; Umrania Y ; Antrobus R ; Nathan JA ; Adams DJ ; Bateman A ; Choudhary JS ; Lyons PA ; Condliffe AM ; Chilvers ER ; Dougan G ; Smith KG J Exp Med 2017[Apr]; 214 (4 ): 1111-1128 PMID28351984 show ga The phagocyte respiratory burst is crucial for innate immunity. The transfer of electrons to oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22phox subunits. Deficiency of either subunit leads to severe immunodeficiency. We describe Eros (essential for reactive oxygen species), a protein encoded by the previously undefined mouse gene bc017643, and show that it is essential for host defense via the phagocyte NAPDH oxidase. Eros is required for expression of the NADPH oxidase components, gp91phox and p22phox Consequently, Eros-deficient mice quickly succumb to infection. Eros also contributes to the formation of neutrophil extracellular traps (NETS) and impacts on the immune response to melanoma metastases. Eros is an ortholog of the plant protein Ycf4, which is necessary for expression of proteins of the photosynthetic photosystem 1 complex, itself also an NADPH oxio-reductase. We thus describe the key role of the previously uncharacterized protein Eros in host defense. |Animals [MESH] |Cytochrome b Group/analysis/physiology [MESH] |Endoplasmic Reticulum/metabolism [MESH] |HEK293 Cells [MESH] |Humans [MESH] |Immunity, Innate [MESH] |Macrophages/immunology [MESH] |Membrane Glycoproteins/analysis/physiology [MESH] |Membrane Proteins/*physiology [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH] |NADPH Oxidase 2 [MESH] |NADPH Oxidases/analysis/physiology [MESH] |Neutrophils/immunology [MESH] |Phagocytes/*physiology [MESH] |Phagocytosis [MESH] |Reactive Oxygen Species/*metabolism [MESH]Eros is a novel transmembrane protein that controls the phagocyte resp(epmc).pdf DeepDyve Pubget Overpricing