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10.1084/jem.20160311

http://scihub22266oqcxt.onion/10.1084/jem.20160311
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C5379968!5379968!28289053
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suck abstract from ncbi


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pmid28289053      J+Exp+Med 2017 ; 214 (4): 1049-64
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  • VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation #MMPMID28289053
  • Fantin A; Lampropoulou A; Senatore V; Brash JT; Prahst C; Lange CA; Liyanage SE; Raimondi C; Bainbridge JW; Augustin HG; Ruhrberg C
  • J Exp Med 2017[Apr]; 214 (4): 1049-64 PMID28289053show ga
  • Fantin et al. show that the VEGF isoform VEGF165 signals through a complex of VEGFR2 and NRP1, in which the NRP1 cytoplasmic domain promotes the ABL-mediated activation of SRC family kinases to evoke a hyperpermeability response, a known cause of pathological edema.
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