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10.7554/eLife.23493 http://scihub22266oqcxt.onion/10.7554/eLife.23493 C5378475!5378475!28290982     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       eLife 2017 ; 6 (ä): ä Nephropedia Template TP {{tp|p=28290982|t=2017. Mating and male pheromone kill Caenorhabditis males through distinct mechanisms |pdf=|usr=}}{{28290982}} gab.com Text Mating and male pheromone kill Caenorhabditis males through distinct mechanisms JO: eLife http://www.kidney.de/pget.php?&tw=1&pmid=28290982 #FOAvip Differences in longevity between sexes is a mysterious yet general phenomenon across great evolutionary distances. To test the roles of responses to environmental cues and sexual behaviors in longevity regulation, we examined Caenorhabditis male lifespan under solitary, grouped, and mated conditions. We find that neurons and the germline are required for male pheromone-dependent male death. Hermaphrodites with a masculinized nervous system secrete male pheromone and are susceptible to male pheromone killing. Male pheromone-mediated killing is unique to androdioecious Caenorhabditis, and may reduce the number of males in hermaphroditic populations; neither males nor females of gonochoristic species are susceptible to male pheromone killing. By contrast, mating-induced death, which is characterized by germline-dependent shrinking, glycogen loss, and ectopic vitellogenin expression, utilizes distinct molecular pathways and is shared between the sexes and across species. The study of sex- and species-specific regulation of aging reveals deeply conserved mechanisms of longevity and population structure regulation.DOI:http://dx.doi.org/10.7554/eLife.23493.001 Twit Text FOAVip Mating and male pheromone kill Caenorhabditis males through distinct mechanisms ????eLife http://www.kidney.de/pget.php?&tw=1&pmid=28290982 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28290982 #FOAvip English Wikipedia <ref>{{Cite pmid|28290982}}</ref> Mating and male pheromone kill Caenorhabditis males through distinct mechanisms #MMPMID28290982 Shi C; Runnels AM; Murphy CT eLife 2017[]; 6 (ä): ä PMID28290982show ga Differences in longevity between sexes is a mysterious yet general phenomenon across great evolutionary distances. To test the roles of responses to environmental cues and sexual behaviors in longevity regulation, we examined Caenorhabditis male lifespan under solitary, grouped, and mated conditions. We find that neurons and the germline are required for male pheromone-dependent male death. Hermaphrodites with a masculinized nervous system secrete male pheromone and are susceptible to male pheromone killing. Male pheromone-mediated killing is unique to androdioecious Caenorhabditis, and may reduce the number of males in hermaphroditic populations; neither males nor females of gonochoristic species are susceptible to male pheromone killing. By contrast, mating-induced death, which is characterized by germline-dependent shrinking, glycogen loss, and ectopic vitellogenin expression, utilizes distinct molecular pathways and is shared between the sexes and across species. The study of sex- and species-specific regulation of aging reveals deeply conserved mechanisms of longevity and population structure regulation.DOI:http://dx.doi.org/10.7554/eLife.23493.001 äMating and male pheromone kill Caenorhabditis males through distinct m(epmc).pdf DeepDyve Pubget Overpricing