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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Ther+Adv+Urol 2017 ; 9 (3-4): 67-72 Nephropedia Template TP
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Bovine serum albumin?glutaraldehyde (BioGlueŽ) tissue adhesive versus standard renorrhaphy following renal mass enucleation: a retrospective comparison #MMPMID28392835
Bahouth Z; Moskovitz B; Halachmi S; Nativ O
Ther Adv Urol 2017[Mar]; 9 (3-4): 67-72 PMID28392835show ga
Background:: To present the operative and post-operative comparison between patients who underwent tumor-bed closure with sutures compared with bovine serum albumin?glutaraldehyde (BioGlueŽ) tissue sealant only. Methods:: We retrospectively analyzed data from our ongoing database of 507 eligible patients who underwent open NSS nephron-sparing surgery in our department between January 1995 and May 2014. Patients had tumor-bed closure with sealant adhesive (255 patients) or standard suture technique (252 patients). Demographic, clinical and perioperative data were compared between the two groups, by Chi-square test or by Fisher?Irwin exact test for categorical variables, and by t test for differences in means or by Wilcoxon rank sum test for continuous variables. A multivariate analysis was also done. Results:: Patients? baseline characteristics showed similar distribution of the analyzed parameters among both groups, with few differences: younger age in the sealant group (65.4 versus 68.4 years, p = 0.01) and slightly larger mass size in the suture group (4.0 versus 3.9 cm, p = 0.03). Ischemia time was significantly shorter in the sealant group (21.8 versus 27.0 minutes, p = 0001). Blood loss and transfusion rate (0.8% versus 11.9%, p = 0.0001) were significantly less in the sealant group. A multivariate analysis showed date of surgery and blood loss as the major parameters affecting transfusion rate. Conclusions:: Closing the tumor bed with BioGlueŽ tissue adhesive is feasible, safe, can shorten ischemia time and potentially reduce transfusion rate.
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Ther+Adv+Urol 2017 ; 9 (3-4): 67-72
