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10.1177/1756287217697662

http://scihub22266oqcxt.onion/10.1177/1756287217697662
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suck abstract from ncbi


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pmid28392835
      Ther+Adv+Urol 2017 ; 9 (3-4 ): 67-72
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  • Bovine serum albumin-glutaraldehyde (BioGlue(®)) tissue adhesive versus standard renorrhaphy following renal mass enucleation: a retrospective comparison #MMPMID28392835
  • Bahouth Z ; Moskovitz B ; Halachmi S ; Nativ O
  • Ther Adv Urol 2017[Mar]; 9 (3-4 ): 67-72 PMID28392835 show ga
  • BACKGROUND: To present the operative and post-operative comparison between patients who underwent tumor-bed closure with sutures compared with bovine serum albumin-glutaraldehyde (BioGlue(®)) tissue sealant only. METHODS: We retrospectively analyzed data from our ongoing database of 507 eligible patients who underwent open NSS nephron-sparing surgery in our department between January 1995 and May 2014. Patients had tumor-bed closure with sealant adhesive (255 patients) or standard suture technique (252 patients). Demographic, clinical and perioperative data were compared between the two groups, by Chi-square test or by Fisher-Irwin exact test for categorical variables, and by t test for differences in means or by Wilcoxon rank sum test for continuous variables. A multivariate analysis was also done. RESULTS: Patients' baseline characteristics showed similar distribution of the analyzed parameters among both groups, with few differences: younger age in the sealant group (65.4 versus 68.4 years, p = 0.01) and slightly larger mass size in the suture group (4.0 versus 3.9 cm, p = 0.03). Ischemia time was significantly shorter in the sealant group (21.8 versus 27.0 minutes, p = 0001). Blood loss and transfusion rate (0.8% versus 11.9%, p = 0.0001) were significantly less in the sealant group. A multivariate analysis showed date of surgery and blood loss as the major parameters affecting transfusion rate. CONCLUSIONS: Closing the tumor bed with BioGlue(®) tissue adhesive is feasible, safe, can shorten ischemia time and potentially reduce transfusion rate.
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