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10.3892/etm.2017.4104 http://scihub22266oqcxt.onion/10.3892/etm.2017.4104 C5377404!5377404 !28413485     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28413485 &cmd=llinks): Failed to open stream: HTTP request failed! 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Therapeutic efficacy of phentolamine in the management of severe hand, foot and mouth disease combined with pulmonary edema |pdf=|usr=}}{{28413485 }} gab.com Text Therapeutic efficacy of phentolamine in the management of severe hand, foot and mouth disease combined with pulmonary edema JO: Exp Ther Med http://www.kidney.de/pget.php?&tw=1&pmid=28413485 #FOAvip The aim of this study was to examine the effects of phentolamine on severe hand, foot and mouth disease (HFMD) combined with pulmonary edema (PE). From May 2008 to December 2012, 53 children with severe HFMD plus PE were enrolled in the treatment group, receiving phentolamine intravenously at a loading dose of 5 µg/kg/min. The control group comprised 52 children with the same disease who did not receive phentolamine infusion. Data concerning creatine kinase (CK), CK-MB, cardiac troponin I (cTnI), heart rate, systolic blood pressure (SBP) and the duration of ventilation dependence and hospitalization were collected. Adverse events were also recorded. It was found that the phentolamine-treated patients exhibited significantly lower CK, CK-MB and cTnI levels, heart rate and SBP than the controls (P<0.01 for all parameters). The average duration of ventilator dependence and hospitalization was significantly shorter (P<0.01) in the phentolamine group than in the control group. It was also found that the overall mortality rate was lower in the phentolamine group (5.8%) than in the control group (11.5%). No adverse events were observed in either group. Thus, these results offer preliminary evidence that phentolamine reduces mortality and relieves the symptoms of EV71-induced PE. Phentolamine is a potential therapeutic agent for this highly lethal disorder. Twit Text FOAVip Therapeutic efficacy of phentolamine in the management of severe hand, foot and mouth disease combined with pulmonary edema ????Exp Ther Med http://www.kidney.de/pget.php?&tw=1&pmid=28413485 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28413485 #FOAvip English Wikipedia <ref>{{Cite pmid|28413485 }}</ref> Therapeutic efficacy of phentolamine in the management of severe hand, foot and mouth disease combined with pulmonary edema #MMPMID28413485 Yan Z ; Shang Y ; Li F ; Xie F ; Qian H ; Zhang Y ; Yue B Exp Ther Med 2017[Apr]; 13 (4 ): 1403-1407 PMID28413485 show ga The aim of this study was to examine the effects of phentolamine on severe hand, foot and mouth disease (HFMD) combined with pulmonary edema (PE). From May 2008 to December 2012, 53 children with severe HFMD plus PE were enrolled in the treatment group, receiving phentolamine intravenously at a loading dose of 5 µg/kg/min. The control group comprised 52 children with the same disease who did not receive phentolamine infusion. Data concerning creatine kinase (CK), CK-MB, cardiac troponin I (cTnI), heart rate, systolic blood pressure (SBP) and the duration of ventilation dependence and hospitalization were collected. Adverse events were also recorded. It was found that the phentolamine-treated patients exhibited significantly lower CK, CK-MB and cTnI levels, heart rate and SBP than the controls (P<0.01 for all parameters). The average duration of ventilator dependence and hospitalization was significantly shorter (P<0.01) in the phentolamine group than in the control group. It was also found that the overall mortality rate was lower in the phentolamine group (5.8%) than in the control group (11.5%). No adverse events were observed in either group. Thus, these results offer preliminary evidence that phentolamine reduces mortality and relieves the symptoms of EV71-induced PE. Phentolamine is a potential therapeutic agent for this highly lethal disorder. äTherapeutic efficacy of phentolamine in the management of severe hand,(epmc).pdf DeepDyve Pubget Overpricing